Molecular structure of 4-(Aminomethyl)-L-phenylalanine, CAS Number: 150338-20-8
4-(Aminomethyl)-L-phenylalanine (CAS 150338-20-8)
Alternate Names:
L-Phe(4-CH2NH2)-OH; p-(Aminomethyl)-L-Phe-OH
Application:
4-(Aminomethyl)-L-phenylalanine is a noncanonical aminomethyl derivative of phenylalanine
CAS Number:
150338-20-8
Molecular Weight:
194.23
Molecular Formula:
C10H14N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-(Aminomethyl)-L-phenylalanine is a noncanonical aminomethyl derivative of the amino acid phenylalanine. It has demonstrated 20 to 30-fold higher affinity for the cucurbit[7]uril (Q7) receptor.
4-(Aminomethyl)-L-phenylalanine (CAS 150338-20-8) References
- Nanomolar binding of peptides containing noncanonical amino acids by a synthetic receptor. | Logsdon, LA., et al. 2011. J Am Chem Soc. 133: 17087-92. PMID: 21967539
- Phenylalanine and Phenylglycine Analogues as Arginine Mimetics in Dengue Protease Inhibitors. | Weigel, LF., et al. 2015. J Med Chem. 58: 7719-33. PMID: 26367391
- Ribosomal Incorporation of Aromatic Oligoamides as Peptide Sidechain Appendages. | Tsiamantas, C., et al. 2020. Angew Chem Int Ed Engl. 59: 4860-4864. PMID: 31894626
- A General Supramolecular Approach to Regulate Protein Functions by Cucurbit[7]uril and Unnatural Amino Acid Recognition. | Cao, W., et al. 2021. Angew Chem Int Ed Engl. 60: 11196-11200. PMID: 33580548
- A convenient synthesis of 4-aminomethyl-L-phenylalanine | Hartman, G. D., & Halczenko, W. 1991. Synthetic communications. 21(20): 2103-2107.
- A simple and inexpensive synthesis of 4-(aminomethyl)-L-phenylalanine | Stokker, G. E., Hoffman, W. F., & Homnick, C. F. 1993. The Journal of Organic Chemistry. 58(18): 5015-5016.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(Aminomethyl)-L-phenylalanine, 250 mg | sc-284056 | 250 mg | $126.00 | |||
4-(Aminomethyl)-L-phenylalanine, 1 g | sc-284056A | 1 g | $233.00 |