4-Aminomethyl-2,5-dimethyl-furan-3-carboxylic acid ethyl ester (CAS 883544-97-6)
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Warfarin Sodium operates as a potent inhibitor of two enzymes, Vitamin K Epoxide Reductase (VKOR) and Cytochrome P450 2C9 (CYP2C9), showcasing its significant role in the biochemical pathways related to coagulation and drug metabolism. The inhibition of VKOR is central to Warfarin′s primary mechanism of action, as this enzyme is essential for the cyclic conversion of vitamin K and its epoxide form. By hindering VKOR activity, Warfarin Sodium effectively reduces the regeneration of vitamin K1, thereby depleting functional vitamin K reserves. This depletion directly impacts the gamma-carboxylation of vitamin K-dependent clotting factors II, VII, IX, and X, along with regulatory proteins C and S, leading to an anticoagulant effect by diminishing the clotting cascade′s efficiency.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Aminomethyl-2,5-dimethyl-furan-3-carboxylic acid ethyl ester, 500 mg | sc-315928 | 500 mg | $260.00 |