Molecular structure of 4-Aminoimidazole Dihydrochloride, CAS Number: 4919-03-3 (free base)
4-Aminoimidazole Dihydrochloride (CAS 111005-19-7)
Alternate Names:
5-Amino-1H-imidazole Dihydrochloride
Application:
4-Aminoimidazole Dihydrochloride is a building block for the synthesis of B12-analogs
CAS Number:
111005-19-7
Molecular Weight:
156.01
Molecular Formula:
C3H5N3•2HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
4-Aminoimidazole Dihydrochloride (4-AI 2HCl) is used as a building block for the synthesis of vitamin B12-analogs via Eubacterium limosu. It acts as a competitive inhibitor of the enzymes acetylcholinesterase and tyrosine hydroxylase, which are involved in the breakdown of the neurotransmitters acetylcholine and dopamine, respectively. It interacts with certain receptors, such as the glutamate receptor. 4-Aminoimidazole Dihydrochloride may act to affect the metabolism of various compounds, such as glucose and fatty acids.
4-Aminoimidazole Dihydrochloride (CAS 111005-19-7) References
- Purine fermentation by Clostridium cylindrosporum. III. 4-Amino-5-imidazolecarboxylic acid and 4-aminoimidazole. | RABINOWITZ, JC. 1956. J Biol Chem. 218: 175-87. PMID: 13278326
- Identification of Aminoimidazole and Aminothiazole Derivatives as Src Family Kinase Inhibitors. | Francini, CM., et al. 2015. ChemMedChem. 10: 2027-41. PMID: 26514807
- Gold-Catalyzed Formal [3 + 2] Cycloaddition of Ynamides with 4,5-Dihydro-1,2,4-oxadiazoles: Synthesis of Functionalized 4-Aminoimidazoles. | Xu, W., et al. 2017. Org Lett. 19: 3307-3310. PMID: 28548862
- Optimization of Aminoimidazole Derivatives as Src Family Kinase Inhibitors. | Francini, CM., et al. 2018. Molecules. 23: PMID: 30227617
- Photochemistry of diazonium salts. 3. A new and facile synthesis of 4-fluoroimidazoles. | Kirk, KL. and Cohen, LA. 1973. J Org Chem. 38: 3647-8. PMID: 4780830
- Photochemical decomposition of diazonium fluoroborates. Application to the synthesis of ring-fluorinated imidazoles. | Kirk, KL. and Cohen, LA. 1971. J Am Chem Soc. 93: 3060-1. PMID: 5095273
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Aminoimidazole Dihydrochloride, 50 mg | sc-391992 | 50 mg | $310.00 |