Date published: 2026-4-24

1-800-457-3801

SCBT Portrait Logo
Seach Input

4-Aminocinnamic Acid (CAS 2393-18-2)

0.0(0)
Write a reviewAsk a question

Alternate Names:
(E)-3-(4-Aminophenyl)acrylic Acid
CAS Number:
2393-18-2
Molecular Weight:
163.17
Molecular Formula:
C9H9NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4-Aminocinnamic acid, abbreviated as 4-ACA, is utilized in the synthesis of other compounds like cinnamates and amides. The unique structure and reactivity of 4-Aminocinnamic acid make it an indispensable compound in numerous applications. It is widely used in scientific research, particularly as a valuable intermediate in the synthesis of a myriad of compounds. Additionally, it′s used in the synthesis of various peptides and peptidomimetics, which are significant in the development of new compounds. While the exact mechanism of action of 4-Aminocinnamic acid isn′t completely understood, it′s postulated that the compound behaves as a nucleophile, interacting with electrophilic species such as carbonyl compounds and aldehydes. This reaction is thought to be responsible for the formation of cinnamates and amides, which are critical in the synthesis of various compounds.


4-Aminocinnamic Acid (CAS 2393-18-2) References

  1. Synthesis of pyrazoles and isoxazoles as potent alpha(v)beta3 receptor antagonists.  |  Penning, TD., et al. 2006. Bioorg Med Chem Lett. 16: 3156-61. PMID: 16621534
  2. Engineering cell factories for producing building block chemicals for bio-polymer synthesis.  |  Tsuge, Y., et al. 2016. Microb Cell Fact. 15: 19. PMID: 26794242
  3. Bioprocessing of bio-based chemicals produced from lignocellulosic feedstocks.  |  Kawaguchi, H., et al. 2016. Curr Opin Biotechnol. 42: 30-39. PMID: 26970511
  4. Microbial conversion of biomass into bio-based polymers.  |  Kawaguchi, H., et al. 2017. Bioresour Technol. 245: 1664-1673. PMID: 28688739
  5. Novel polycondensed biopolyamide generated from biomass-derived 4-aminohydrocinnamic acid.  |  Kawasaki, Y., et al. 2018. Appl Microbiol Biotechnol. 102: 631-639. PMID: 29150705
  6. Fluorinated and Bio-Based Polyamides with High Transparencies and Low Yellowness Index.  |  Takada, K., et al. 2018. Polymers (Basel). 10: PMID: 30961236
  7. Molecular Design of Soluble Biopolyimide with High Rigidity.  |  Dwivedi, S. and Kaneko, T. 2018. Polymers (Basel). 10: PMID: 30966403
  8. Electric Volume Resistivity for Biopolyimide Using 4,4'-Diamino-α-truxillic acid and 1,2,3,4-Cyclobutanetetracarboxylic dianhydride.  |  Kato, S., et al. 2019. Polymers (Basel). 11: PMID: 31554214
  9. Mutagenic potency of some conjugated nitroaromatic compounds and its relationship to structure.  |  Mullin, CA., et al. 1987. Mutat Res. 188: 267-74. PMID: 3302696
  10. Visualizing a Single-Crystal-to-Single-Crystal [2+2] Photodimerization through its Lattice Dynamics: An Experimental and Theoretical Investigation.  |  Giunchi, A., et al. 2022. Chemphyschem. 23: e202200168. PMID: 35393755
  11. High-temperature resistant water-soluble polymers derived from exotic amino acids.  |  Dwivedi, S., et al. 2020. RSC Adv. 10: 38069-38074. PMID: 35515151
  12. Effects of biopolyimide molecular design on their silica hybrids thermo-mechanical, optical and electrical properties.  |  Dwivedi, S., et al. 2018. RSC Adv. 8: 14009-14016. PMID: 35539300
  13. Fermentative production of 2-(4-aminophenyl)ethylamine to synthesize a novel heat-resistant biopolyurea.  |  Minakawa, H., et al. 2022. Biosci Biotechnol Biochem. 86: 1114-1121. PMID: 35612977
  14. Absorption and metabolism of 5-(4-nitrophenyl)-2,4-pentadienal (Spydust).  |  Burka, LT., et al. 1987. Toxicol Appl Pharmacol. 87: 121-6. PMID: 3798448
  15. Phenol derivatives as enhancers and inhibitors of luminol-H2O2-horseradish peroxidase chemiluminescence.  |  Navas Díaz, A., et al. 1998. J Biolumin Chemilumin. 13: 75-84. PMID: 9633010

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Aminocinnamic Acid, 5 g

sc-289915
5 g
$265.00

4-Aminocinnamic Acid, 25 g

sc-289915A
25 g
$663.00