4-Aminobutyric acid-2,2,3,3,4,4-d6 (CAS 70607-85-1)
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4-Aminobutyric acid-2,2,3,3,4,4-d6 is a modified version of 4-aminobutyric acid (GABA), a vital neurotransmitter in the central nervous system. It′s a deuterated form of 4-Aminobutyric acid-2,2,3,3,4,4. Compared to natural GABA, 4-Aminobutyric acid-2,2,3,3,4,4-d6 offers several advantages, including enhanced metabolic stability, heightened sensitivity to analytical methods, and increased stability during laboratory experiments. 4-Aminobutyric acid-2,2,3,3,4,4-d6 offers a non-radioactive way to trace the biochemical pathways and interactions of GABA within biological systems, providing insights into its function, metabolism, and the effects of external compounds on GABAergic signaling. This can be particularly useful in neuroscience research, where understanding GABA′s role is crucial.
4-Aminobutyric acid-2,2,3,3,4,4-d6 (CAS 70607-85-1) References
- Low posttrauma GABA plasma levels as a predictive factor in the development of acute posttraumatic stress disorder. | Vaiva, G., et al. 2004. Biol Psychiatry. 55: 250-4. PMID: 14744465
- Characteristics of endogenous γ-aminobutyric acid (GABA) in human platelets: functional studies of a novel collagen glycoprotein VI inhibitor. | Lin, KH., et al. 2014. J Mol Med (Berl). 92: 603-14. PMID: 24626935
- Increased nutrient availability in dense breast tissue of postmenopausal women in vivo. | Abrahamsson, A., et al. 2017. Sci Rep. 7: 42733. PMID: 28198437
- Rapid analysis of glutamate, glutamine and GABA in mice frontal cortex microdialysis samples using HPLC coupled to electrospray tandem mass spectrometry. | Defaix, C., et al. 2018. J Pharm Biomed Anal. 152: 31-38. PMID: 29414016
- Different Circulating Trace Amine Profiles in De Novo and Treated Parkinson's Disease Patients. | D'Andrea, G., et al. 2019. Sci Rep. 9: 6151. PMID: 30992490
- Pyridox(am)ine 5'-phosphate oxidase (PNPO) deficiency in zebrafish results in fatal seizures and metabolic aberrations. | Ciapaite, J., et al. 2020. Biochim Biophys Acta Mol Basis Dis. 1866: 165607. PMID: 31759955
- LC-MS/MS analysis of twelve neurotransmitters and amino acids in mouse cerebrospinal fluid. | Blanco, ME., et al. 2020. J Neurosci Methods. 341: 108760. PMID: 32428622
- Imaging of Neurotransmitters and Small Molecules in Brain Tissues Using Laser Desorption/Ionization Mass Spectrometry Assisted with Zinc Oxide Nanoparticles. | Chen, C., et al. 2021. J Am Soc Mass Spectrom. 32: 1065-1079. PMID: 33783203
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Aminobutyric acid-2,2,3,3,4,4-d6, 100 mg | sc-310978 | 100 mg | $690.00 |