4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid (CAS 124168-73-6)
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4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid is a compound often studied in the field of protease inhibition. It is specifically designed to mimic the transition state of peptide hydrolysis, which makes it useful for investigating the activity of proteolytic enzymes. Researchers use this compound to understand the substrate specificity and catalytic mechanisms of proteases, particularly those involved in regulatory pathways. Its structure, which incorporates a hydroxamic acid moiety, allows for the formation of a tight-binding complex with the active site of certain proteases, making it an interesting candidate for studying enzyme kinetics and dynamics. Additionally, 4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid is involved in the design of protease assays that are critical for the screening of enzyme inhibitors and the exploration of their potential applications in various fields of biochemistry and molecular biology.
4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid (CAS 124168-73-6) References
- Decreased Invasion of Urothelial Carcinoma of the Bladder by Inhibition of Matrix-Metalloproteinase 7. | Bolenz, C., et al. 2018. Bladder Cancer. 4: 67-75. PMID: 29430508
- Potential of Matrix Metalloproteinase Inhibitors for the Treatment of Local Tissue Damage Induced by a Type P-I Snake Venom Metalloproteinase. | Preciado, LM., et al. 2019. Toxins (Basel). 12: PMID: 31861940
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Aminobenzoyl-Gly-Pro-D-Leu-D-Ala hydroxamic acid, 5 mg | sc-214226 | 5 mg | $275.00 |