Date published: 2026-2-2

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4-Amino-6-hydroxy-2-mercaptopyrimidine (CAS 65802-56-4)

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Alternate Names:
6-Amino-2-thiouracil
Application:
4-Amino-6-hydroxy-2-mercaptopyrimidine is a precursor to A3 adenosine receptor antagonists
CAS Number:
65802-56-4
Molecular Weight:
143.17
Molecular Formula:
C4H5N3OS
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Derivatives of 6-Amino-2-thiouracil as novel, potent, and selective A3 adenosine receptor antagonists.


4-Amino-6-hydroxy-2-mercaptopyrimidine (CAS 65802-56-4) References

  1. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors.  |  Fredholm, BB., et al. 2001. Pharmacol Rev. 53: 527-52. PMID: 11734617
  2. Purification, substrate range, and metal center of AtzC: the N-isopropylammelide aminohydrolase involved in bacterial atrazine metabolism.  |  Shapir, N., et al. 2002. J Bacteriol. 184: 5376-84. PMID: 12218024
  3. Elevated expression of A3 adenosine receptors in human colorectal cancer is reflected in peripheral blood cells.  |  Gessi, S., et al. 2004. Clin Cancer Res. 10: 5895-901. PMID: 15355922
  4. Different approaches for assaying melanosome transfer.  |  Berens, W., et al. 2005. Pigment Cell Res. 18: 370-81. PMID: 16162177
  5. Progress in the pursuit of therapeutic adenosine receptor antagonists.  |  Moro, S., et al. 2006. Med Res Rev. 26: 131-59. PMID: 16380972
  6. Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models.  |  Tafi, A., et al. 2006. J Med Chem. 49: 4085-97. PMID: 16821770
  7. Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.  |  Cosimelli, B., et al. 2008. J Med Chem. 51: 1764-70. PMID: 18269230
  8. Non-Nucleoside Agonists of the Adenosine Receptors: An Overview.  |  Dal Ben, D., et al. 2019. Pharmaceuticals (Basel). 12: PMID: 31597388
  9. Effect of Indole-2-carboxylic Acid on the Self-Corrosion and Discharge Activity of Aluminum Alloy Anode in Alkaline Al-Air Battery.  |  Guo, L., et al. 2023. Molecules. 28: PMID: 37241932
  10. Adenosine receptors: new opportunities for future drugs.  |  Poulsen, SA. and Quinn, RJ. 1998. Bioorg Med Chem. 6: 619-41. PMID: 9681130

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Amino-6-hydroxy-2-mercaptopyrimidine, 25 g

sc-217301
25 g
$115.00