Date published: 2026-1-31

1-800-457-3801

SCBT Portrait Logo
Seach Input

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole (CAS 1750-12-5)

5.0(1)
Write a reviewAsk a question

Alternate Names:
4-Amino-3-hydrazino-4h-[1,2,4]triazole-5-thiol
Application:
4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole is a reagent used in the determination of aldehydes and other reactive chemicals
CAS Number:
1750-12-5
Purity:
≥98%
Molecular Weight:
146.17
Molecular Formula:
C2H6N6S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole, also called Purpald, is a reagent used in the determination of aldehydes and other reactive chemicals. It has versatile applications, including its use in the synthesis of compounds and as a colorimetric and pH indicator. Additionally, it may act to act as a chelating agent, antioxidant, and antimicrobial agent.


4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole (CAS 1750-12-5) References

  1. Comparison of three colorimetric reagents in the determination of methanol with alcohol oxidase. Application to the assay of pectin methylesterase.  |  Anthon, GE. and Barrett, DM. 2004. J Agric Food Chem. 52: 3749-53. PMID: 15186092
  2. Determination of formaldehyde in aqueous solutions by a novel fluorescence energy transfer system.  |  Wang, L., et al. 2010. Analyst. 135: 2139-43. PMID: 20577665
  3. Terbium (III) chelate complexes as fluorescence energy transfer donor in the determination of formaldehyde in aqueous solutions.  |  Chen, H., et al. 2011. Spectrochim Acta A Mol Biomol Spectrosc. 78: 371-4. PMID: 21081282
  4. A small-scale, inexpensive method for detecting formaldehyde or methanol in biochemical reactions containing interfering substances.  |  Jiang, WZ., et al. 2013. Anal Biochem. 442: 146-8. PMID: 23938775
  5. Silsesquioxane organofunctionalized with 4-amino-3-hydrazino-5-mercapto-1,2,4-triazole: Preparation and subsequent reaction with silver and potassium hexacyanoferrate(III) for detection of L-cysteine.  |  do Carmo, DR., et al. 2015. Mater Sci Eng C Mater Biol Appl. 57: 24-30. PMID: 26354236
  6. Detection of Sulfide Using Mercapto Tetrazine-Protected Fluorescent Gold Nanodots: Preparation of Paper-Based Testing Kit for On-Site Monitoring.  |  Vasimalai, N., et al. 2018. ACS Appl Mater Interfaces. 10: 1634-1645. PMID: 29271189
  7. A nanoporous palladium(II) bridged coordination polymer acting as a peroxidase mimic in a method for visual detection of glucose in tear and saliva.  |  Vinita,., et al. 2018. Mikrochim Acta. 185: 245. PMID: 29610983
  8. A spectrophotometric method for determination of catalase activity in small tissue samples.  |  Johansson, LH. and Borg, LA. 1988. Anal Biochem. 174: 331-6. PMID: 3064653
  9. Design, Synthesis, and Targeted Delivery of Fluorescent 1,2,4-Triazole-Peptide Conjugates to Pediatric Brain Tumor Cells.  |  Ajmal, M., et al. 2019. ACS Omega. 4: 22280-22291. PMID: 31909311
  10. Flexible and Reusable Ag Coated TiO2 Nanotube Arrays for Highly Sensitive SERS Detection of Formaldehyde.  |  Zhu, T., et al. 2020. Molecules. 25: PMID: 32155919
  11. A new colorimetric method for the determination of free fatty acids with acyl-CoA synthetase and acyl-CoA oxidase.  |  Hosaka, K., et al. 1981. J Biochem. 89: 1799-803. PMID: 7287653
  12. A rapid formaldehyde assay using purpald reagent: application under periodation conditions.  |  Quesenberry, MS. and Lee, YC. 1996. Anal Biochem. 234: 50-5. PMID: 8742081
  13. Purpald (4-Amino-3-hydrazino-5-mercapto-1, 2, 4-triazole) as a Reagent for Post-Column Derivatization of Neutral Monosaccharides in High Pressure Liquid Chromatography  |  M. J. Del Nozal, et al. 1993. Journal of Liquid Chromatography. 16: 1105-1116.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole, 10 g

sc-209923
10 g
$143.00

What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. This chemical, 4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole: sc-209923, has a white powder appearance.
Answered by: Chemical Support 3
Date published: 2017-01-31
  • y_2026, m_1, d_23, h_8CST
  • bvseo_bulk, prod_bvqa, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasquestionsanswers, tq_1
  • loc_en_US, sid_209923, prod, sort_[SortEntry(order=LAST_APPROVED_ANSWER_SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getContent, 96ms
  • QUESTIONS, PRODUCT
Rated 5 out of 5 by from Various publications cite the use of the reagent 4Various publications cite the use of the reagent 4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole in the determination of aldehydes and other reactive chemicals. -SCBT Publication Review
Date published: 2015-02-20
  • y_2026, m_1, d_23, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_209923, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getReviews, 16ms
  • REVIEWS, PRODUCT
4-Amino-3-hydrazino-5-mercapto-1,2,4-triazole is rated 5.0 out of 5 by 1.
  • y_2026, m_1, d_23, h_8
  • bvseo_bulk, prod_bvrr, vn_bulk_3.0.42
  • cp_1, bvpage1
  • co_hasreviews, tv_0, tr_1
  • loc_en_US, sid_209923, prod, sort_[SortEntry(order=SUBMISSION_TIME, direction=DESCENDING)]
  • clientName_scbt
  • bvseo_sdk, java_sdk, bvseo-4.0.0
  • CLOUD, getAggregateRating, 102ms
  • REVIEWS, PRODUCT