4-Amino-2-benzooxazol-2-yl-phenol (CAS 62129-02-6)
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Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is a linear polypeptide antibiotic with a mixture of gramicidin A, B, C, and D. Gramicidin D is a channel-forming ionophore that flip-flops slowly across the membrane and is a known Pgp substrate and surprisingly was found to inhibit Pgp ATPase activity. This inhibition was reversed by other Pgp substrates suggesting a common drug binding site among MDR substrate-type drugs and chemosensitizers. Gramicidin from Bacillus aneurinolyticus (Bacillus brevis) is active against the Gram-positive bacterium S. aureus but not Gram-negative E. coli. It inhibits growth of bacteria by forming pores and channels in the cell wall, which increases its permeability to monovalent cations.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-Amino-2-benzooxazol-2-yl-phenol, 500 mg | sc-315736 | 500 mg | $248.00 |