Date published: 2026-4-29

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4-Acryloylmorpholine (CAS 5117-12-4)

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Alternate Names:
4-(1-Oxo-2-propenyl)morpholine, 1-Morpholinoprop-2-en-1-one
CAS Number:
5117-12-4
Molecular Weight:
141.17
Molecular Formula:
C7H11NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4-Acryloylmorpholine is a chemical compound that functions as a reactive monomer in polymerization reactions. It acts as a crosslinking agent in the synthesis of polymers, forming covalent bonds between polymer chains to create a network structure. 4-Acryloylmorpholine′s mode of action involves the addition of its acryloyl group to polymer chains, leading to the formation of a three-dimensional network that enhances the mechanical and thermal properties of the resulting polymer. 4-Acryloylmorpholine facilitates the production of polymers with improved strength, flexibility, and resistance to heat and chemicals, making it a useful component in the development of advanced materials for various industrial applications.


4-Acryloylmorpholine (CAS 5117-12-4) References

  1. Cobalt-catalyzed reductive Mannich reactions of 4-acryloylmorpholine with N-tosyl aldimines.  |  Prieto, O. and Lam, HW. 2008. Org Biomol Chem. 6: 55-7. PMID: 18075647
  2. Surface design for controlled crystallization: the role of surface chemistry and nanoscale pores in heterogeneous nucleation.  |  Diao, Y., et al. 2011. Langmuir. 27: 5324-34. PMID: 21480598
  3. Binding affinity of a small molecule to an amorphous polymer in a solvent. Part 2: preferential binding to local sites on a surface.  |  Chunsrivirot, S., et al. 2011. Langmuir. 27: 12396-404. PMID: 21936549
  4. Diisopinocampheylborane-mediated reductive aldol reactions: highly enantio- and diastereoselective synthesis of syn aldols from N-acryloylmorpholine.  |  Nuhant, P., et al. 2013. Angew Chem Int Ed Engl. 52: 8703-7. PMID: 23818095
  5. Effects of pendant-like hydrophilic monomers on the adsorption properties of reversed-phase-type sorbents for solid-phase extraction.  |  Murakami, H., et al. 2019. Anal Chim Acta. 1075: 106-111. PMID: 31196415
  6. Rapid Open-Air Digital Light 3D Printing of Thermoplastic Polymer.  |  Deng, S., et al. 2019. Adv Mater. 31: e1903970. PMID: 31402545
  7. Enzyme-initiated free radical polymerizations of vinyl monomers using horseradish peroxidase.  |  Rodriguez, KJ., et al. 2019. Methods Enzymol. 627: 249-262. PMID: 31630743
  8. Clay-based nanocomposite hydrogel with attractive mechanical properties and sustained bioactive ion release for bone defect repair.  |  Zhai, X., et al. 2021. J Mater Chem B. 9: 2394-2406. PMID: 33625433
  9. New Copolymers of Vinylphosphonic Acid with Hydrophilic Monomers and Their Eu3+ Complexes.  |  Nazarova, O., et al. 2022. Polymers (Basel). 14: PMID: 35160579
  10. Outbreak of occupational allergic contact dermatitis from a smartphone screen protector glue.  |  Herreros-Montejano, F., et al. 2022. Contact Dermatitis. 87: 53-61. PMID: 35184294
  11. Nonoccupational Allergic Contact Dermatitis to 4-Acryloylmorpholine in Smartwatch Screen Protectors Glue.  |  Gatica-Ortega, ME., et al. Dermatitis. 33: 429-434. PMID: 35674508
  12. Synthesis and Anti-influenza Activity of Vinylphosphonic Acid (Co)polymers.  |  Zarubaev, VV., et al. 2022. Dokl Biochem Biophys. 506: 227-230. PMID: 36303058
  13. Modulating the Coordination Environment of Lithium Bonds for High Performance Polymer Electrolyte Batteries.  |  Tian, Z., et al. 2023. ACS Nano. 17: 3786-3796. PMID: 36745186

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-Acryloylmorpholine, 5 g

sc-276993
5 g
$77.00