Date published: 2025-9-26

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(4-acetylphenyl)acetic acid (CAS 7398-52-9)

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CAS Number:
7398-52-9
Molecular Weight:
178.18
Molecular Formula:
C10H10O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(4-Acetylphenyl)acetic acid, often referred to as 4-APAA, is an organic compound that falls under the category of phenylacetic acids. (4-Acetylphenyl)acetic acid is a intermediate in the creation of diverse compounds, encompassing those used in the agricultural sector, fragrance industry, and more. It has found extensive use in scientific research, contributing to the exploration of biochemical and physiological impacts. This compound has been leveraged for studying the metabolism of phenylacetic acids in mammals, and for understanding the properties of phenylacetic acid derivatives. Additionally, it has been utilized in the synthesis research of other compounds, such as those used in agriculture and the creation of fragrances. Despite its wide use, the exact mechanism of (4-Acetylphenyl)acetic acid′s action is not entirely known. It is theorized to function as an inhibitor of certain enzymes implicated in the metabolism of phenylacetic acids, including phenylalanine hydroxylase and tyrosine hydroxylase. Concurrently, it is suspected of behaving as an agonist of G-protein coupled receptors like the adenosine A2A receptor.


(4-acetylphenyl)acetic acid (CAS 7398-52-9) References

  1. Substrate activation by acyl-CoA dehydrogenases: transition-state stabilization and pKs of involved functional groups.  |  Vock, P., et al. 1998. Biochemistry. 37: 1848-60. PMID: 9485310

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(4-acetylphenyl)acetic acid, 1 g

sc-349017
1 g
$877.00

(4-acetylphenyl)acetic acid, 5 g

sc-349017A
5 g
$1632.00