4-Acetylamino-Kdn2en, iso-Neu4Ac2en (CAS 263155-11-9)

4-Acetylamino-Kdn2en, iso-Neu4Ac2en, is a synthetic sialic acid derivative that has garnered significant attention in glycobiology research. Sialic acids play crucial roles in various biological processes, including cell-cell interactions, immune responses, and pathogen-host interactions. 4-Acetylamino-Kdn2en, iso-Neu4Ac2en, is structurally similar to naturally occurring sialic acids, enabling researchers to investigate their biological functions and interactions with sialic acid-binding proteins (siglecs). Studies have demonstrated that this compound can serve as a substrate analog for sialidases, enzymes responsible for the removal of sialic acids from glycoconjugates. By utilizing 4-Acetylamino-Kdn2en, iso-Neu4Ac2en, researchers can assess the activity and specificity of sialidases, elucidating their roles in cellular processes and disease pathogenesis. Additionally, this compound has been utilized in the development of sialic acid mimetics and inhibitors targeting sialic acid-binding proteins, such as siglecs and viral hemagglutinins. Through structural modifications and biochemical assays, researchers aim to enhance the selectivity and potency of sialidase inhibitors for potential applications. Moreover, 4-Acetylamino-Kdn2en, iso-Neu4Ac2en, serves as a valuable tool in studying sialic acid-mediated host-pathogen interactions, including viral entry and immune evasion strategies. Overall, this compound holds promise for advancing our understanding of sialic acid biology and developing novel strategies for targeting sialic acid-related pathways.