4-Acetamidophenyl β-D-Glucuronic Acid Methyl Ester (CAS 570394-17-1)

4-Acetamidophenyl β-D-Glucuronic Acid Methyl Ester is a synthesized ester derivative of glucuronic acid linked to an acetamidophenyl group. This compound is particularly significant in the realm of glycoscience for studying the interactions and modifications of glycosaminoglycans (GAGs), crucial components of the extracellular matrix in cells. Its structure enables researchers to investigate the specific biochemical pathways involved in the metabolism of glucuronic acid, a key component of many biologically important polysaccharides including hyaluronan and heparan sulfate. By mimicking the natural substrates of enzymes such as glucuronidases and glucuronyl transferases, this compound helps explain the mechanism of action of these enzymes, which are vital for the synthesis and breakdown of GAGs. Additionally, the acetamidophenyl group serves as a useful tag for detection and analysis in experimental setups, aiding in the monitoring and quantification of enzymatic activities in vitro. Research using this chemical focuses on understanding how modifications in glucuronic acid derivatives influence cellular communication, protein binding, and signal transduction, thereby contributing to fundamental insights into cellular processes.