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BML-267 is a potent and selective PTP1B (protein tyrosine phosphatase 1B) inhibitor (IC50=11 muM)1. A similar N-des-methyl analog has been reported and has been used to probe the mechanism of PTP1B-mediated inhibition of leptin signaling. BML-267 have limited cell permeability. A cell permeable diethyl ester prodrug of BML-267 compound is available.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(4,6-Dimethyl-pyrimidin-2-ylsulfanyl)-acetic acid, 500 mg | sc-317196 | 500 mg | $240.00 |