Date published: 2026-4-24

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4,6-Dimethoxysalicylaldehyde (CAS 708-76-9)

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Alternate Names:
2,4-Dimethoxy-6-hydroxybenzaldehyde; 4,6-Dimethoxy-2-hydroxybenzaldehyde
Application:
4,6-Dimethoxysalicylaldehyde is a useful antifungal against certain yeasts and a precursor to hexahydrodibenzofuran
CAS Number:
708-76-9
Molecular Weight:
182.17
Molecular Formula:
C9H10O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,6-Dimethoxysalicylaldehyde is widely utilized in the synthesis of pharmaceuticals, dyes, and various organic compounds, showcasing its versatility. Moreover, it serves as a precursor in the synthesis of polymers and other compounds of interest. Additionally, it has played a pivotal role in the synthesis of peptides and proteins. One remarkable attribute of 4,6-Dimethoxysalicylaldehyde lies in its potent inhibition of the enzyme tyrosinase. Tyrosinase is responsible for the synthesis of melanin, the pigment found in the skin. Through its inhibitory action on tyrosinase, 4,6-Dimethoxysalicylaldehyde effectively reduces the production of melanin. Furthermore, the inhibitory effects of 4,6-Dimethoxysalicylaldehyde extend beyond tyrosinase. It has been observed to impede the growth of diverse fungi, bacteria, and even certain viruses. This property highlights its potential as useful in combating these harmful microorganisms.


4,6-Dimethoxysalicylaldehyde (CAS 708-76-9) References

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  2. The ortho backbone amide linker (o-BAL) is an easily prepared and highly acid-labile handle for solid-phase synthesis.  |  Boas, U., et al. 2002. J Comb Chem. 4: 223-8. PMID: 12005482
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  6. QSTR with extended topochemical atom (ETA) indices. 14. QSAR modeling of toxicity of aromatic aldehydes to Tetrahymena pyriformis.  |  Roy, K. and Das, RN. 2010. J Hazard Mater. 183: 913-22. PMID: 20739120
  7. {3,3',5,5'-Tetra-meth-oxy-2,2'-[ethane-1,2-diylbis(nitrilo-methyl-idyne)]diphenolato}nickel(II).  |  Assey, GE., et al. 2010. Acta Crystallogr Sect E Struct Rep Online. 66: m620. PMID: 21579278
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,6-Dimethoxysalicylaldehyde, 1 g

sc-238993
1 g
$34.00

4,6-Dimethoxysalicylaldehyde, 5 g

sc-238993A
5 g
$131.00

4,6-Dimethoxysalicylaldehyde, 10 g

sc-238993B
10 g
$208.00

4,6-Dimethoxysalicylaldehyde, 25 g

sc-238993C
25 g
$416.00