Date published: 2025-10-16

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4-{[6-(3-Fluorophenyl)pyridazin-3-yl]-amino}benzoic acid

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Molecular Weight:
309.3
Molecular Formula:
C17H12FN3O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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XAV939 is a potent, small molecule inhibitor of tankyrase 1 (TNKS) (IC50 = 11 nM) and tankyrase 2 (IC50 = 4 nM). By inhibiting TNKS activity, XAV939 increases the protein levels of the axin-GSK3β complex and promotes the degradation of beta-catenin in SW480 cells. At concentrations as low as 0.3 muM, XAV939 inhibits colony formation of APC-deficient colorectal cancer cells.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-{[6-(3-Fluorophenyl)pyridazin-3-yl]-amino}benzoic acid, 500 mg

sc-315602
500 mg
$180.00