Date published: 2026-4-24

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4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride (CAS 81864-15-5)

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Alternate Names:
1,3-Benzodioxole-5,6-diamine dihydrochloride; 5,6-Diamino-1,3-benzodioxole dihydrochloride
Application:
4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride is a fluorogenic reagent for α-ketoacids
CAS Number:
81864-15-5
Molecular Weight:
225.07
Molecular Formula:
C7H8N2O22HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride is the dihydrochloride salt preparation of 4,5-Methylenedioxy-1,2-phenylenediamine, a useful fluorogenic probe for a-ketoacids. The diamine functionality of 4,5-Methylenedioxy-1,2-phenylenediamine reacts with a-ketoacids of interest, producing a fluorescent adduct which can then be detected by HPLC.


4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride (CAS 81864-15-5) References

  1. Measurement of sialic acid content on recombinant membrane proteins.  |  Baycin-Hizal, D., et al. 2011. BMC Proc. 5 Suppl 8: P59. PMID: 22373179
  2. Comparative analysis of lipopolysaccharides of pathogenic and intermediately pathogenic Leptospira species.  |  Patra, KP., et al. 2015. BMC Microbiol. 15: 244. PMID: 26518696
  3. Membrane-enclosed multienzyme (MEME) synthesis of 2,7-anhydro-sialic acid derivatives.  |  Monestier, M., et al. 2017. Carbohydr Res. 451: 110-117. PMID: 28851488
  4. Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines.  |  Wratil, PR. and Horstkorte, R. 2017. J Vis Exp.. PMID: 29286437
  5. The impact of sialylation linkage-type on the pharmacokinetics of recombinant butyrylcholinesterases.  |  Chung, CY., et al. 2020. Biotechnol Bioeng. 117: 157-166. PMID: 31544955
  6. An efficient assay for identification and quantitative evaluation of potential polysialyltransferase inhibitors.  |  Guo, X., et al. 2020. Analyst. 145: 4512-4521. PMID: 32412559
  7. The lytic polysaccharide monooxygenase CbpD promotes Pseudomonas aeruginosa virulence in systemic infection.  |  Askarian, F., et al. 2021. Nat Commun. 12: 1230. PMID: 33623002
  8. Analytical comparability assessment on glycosylation of ziv-aflibercept and the biosimilar candidate.  |  Shen, Z., et al. 2021. Int J Biol Macromol. 180: 494-509. PMID: 33684428
  9. Fluorometric high-performance liquid chromatography of N-acetyl- and N-glycolylneuraminic acids and its application to their microdetermination in human and animal sera, glycoproteins, and glycolipids.  |  Hara, S., et al. 1987. Anal Biochem. 164: 138-45. PMID: 3674364

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, 10 mg

sc-214287
10 mg
$156.00

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, 50 mg

sc-214287A
50 mg
$478.00

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, 250 mg

sc-214287B
250 mg
$731.00

4,5-Methylenedioxy-1,2-phenylenediamine dihydrochloride, 1 g

sc-214287C
1 g
$1331.00