Molecular structure of 4-(5-Ethyl-thiophen-2-yl)-5-methyl-thiazol-2-ylamine
4-(5-Ethyl-thiophen-2-yl)-5-methyl-thiazol-2-ylamine
Molecular Weight:
224.35
Molecular Formula:
C10H12N2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Lck Inhibitor is a cell-permeable pyrrolopyrimidine compound that acts as a potent, selective, and ATP-competitive inhibitor of Lck (IC50 at 5 muM ATP = < 1 nM, 2 nM, 70 nM, 1.57 muM and 1.98 muM for lck64-509 Y394, Lckcd pY394, Src, Kdr and Tie-2, respectively IC50 at 1 mM ATP = 16 muM, 66 nM, 126 nM, 420 nM and 5.18 muM for Lck64-509 Y394, Blk, Fyn, Lyn and Csk, respectively). Only minimally affects the activities of other kinases (IC50 = 3.2 muM, > 33 muM, > 50 muM and > 50 muM for EGFR, PKC, CDC2/B and ZAP-70, respectively). Also shown to potently block T-cell receptor-stimulated IL-2 production in vitro (IC50 < 1-40 nM in Jurkat T cells).
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(5-Ethyl-thiophen-2-yl)-5-methyl-thiazol-2-ylamine, 500 mg | sc-314775 | 500 mg | $260.00 |