Date published: 2025-12-31

1-800-457-3801

SCBT Portrait Logo
Seach Input

4,5-Dihydro-2-methoxy-1H-imidazole (CAS 28118-54-9)

0.0(0)
Write a reviewAsk a question

Application:
4,5-Dihydro-2-methoxy-1H-imidazole is a lysine specific derivitization agent
CAS Number:
28118-54-9
Molecular Weight:
100.12
Molecular Formula:
C4H8N2O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4,5-Dihydro-2-methoxy-1H-imidazole (MDHI) is a multifunctional label for use in proteomic studies. MDHI is lysine specific and by increasing the ionization of lysine terminated tryptic fragments it also increases the overall sequence coverage obtained in peptide mapping experiments. It has been used in peptide termini labeling to quantify and identify two differentially labeled states. It can be used after endoproteinase Lys-C digestion.


4,5-Dihydro-2-methoxy-1H-imidazole (CAS 28118-54-9) References

  1. A novel multifunctional labeling reagent for enhanced protein characterization with mass spectrometry.  |  Peters, EC., et al. 2001. Rapid Commun Mass Spectrom. 15: 2387-92. PMID: 11746907
  2. Proteome profiling of human cerebrospinal fluid: exploring the potential of capillary electrophoresis with surface modified capillaries for analysis of complex biological samples.  |  Zuberovic, A., et al. 2008. Eur J Mass Spectrom (Chichester). 14: 249-60. PMID: 18756023
  3. Isobaric peptide termini labeling for MS/MS-based quantitative proteomics.  |  Koehler, CJ., et al. 2009. J Proteome Res. 8: 4333-41. PMID: 19655813

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,5-Dihydro-2-methoxy-1H-imidazole, 250 mg

sc-210177
250 mg
$800.00