Date published: 2025-10-17

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4,5-dehydro Docosahexaenoic Acid (CAS 660429-97-0)

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Application:
4,5-dehydro Docosahexaenoic Acid is a novel analog of DHA
CAS Number:
660429-97-0
Purity:
>98%
Molecular Weight:
326.5
Molecular Formula:
C22H30O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,5-dehydro Docosahexaenoic Acid (DHA) is a chemically modified form of Docosahexaenoic Acid, a highly unsaturated omega-3 fatty acid crucial for the structural component of cellular membranes, particularly in neural and retinal tissues. This specific derivative introduces a double bond between the 4th and 5th carbon atoms, altering the typical molecular structure of DHA. This modification impacts the chemical′s physical properties and its interaction within biological systems, particularly affecting how it integrates into lipid membranes and interacts with other lipid molecules. In research, 4,5-dehydro DHA is used primarily to study the impact of structural changes in fatty acids on their physical and biological functions. The introduction of an additional double bond may influence the molecule′s fluidity and flexibility, which are critical parameters in understanding cell membrane dynamics, signaling pathways, and the overall behavior of lipids in cellular environments. Researchers utilize this compound to explore the mechanisms by which modified fatty acids can affect membrane properties, enzyme interactions, and signal transduction processes. These studies provide insights into the role of fatty acids in maintaining cellular structure and function, and how slight modifications can significantly alter these biological properties.


4,5-dehydro Docosahexaenoic Acid (CAS 660429-97-0) References

  1. Use of metabolomics and lipidomics to evaluate the hypocholestreolemic effect of Proanthocyanidins from grape seed in a pig model.  |  Quifer-Rada, P., et al. 2016. Mol Nutr Food Res. 60: 2219-2227. PMID: 27240545
  2. Study of the metabolomics characteristics of patients with metabolic syndrome based on liquid chromatography quadrupole time-of-flight mass spectrometry.  |  Wu, N., et al. 2018. Ann Endocrinol (Paris). 79: 37-44. PMID: 29246383
  3. Sishen Pill Ameliorates Dextran Sulfate Sodium (DSS)-Induced Colitis with Spleen-Kidney Yang Deficiency Syndromes: Role of Gut Microbiota, Fecal Metabolites, Inflammatory Dendritic Cells, and TLR4/NF-κB Pathway.  |  Ge, W., et al. 2022. Evid Based Complement Alternat Med. 2022: 6132289. PMID: 36310616
  4. Maternal voluntary wheel running modulates glucose homeostasis, the gut microbiota and its derived fecal metabolites in offspring.  |  Zhang, L., et al. 2023. Clin Sci (Lond). 137: 1151-1166. PMID: 37505199
  5. Dynamic molecular choreography induced by acute heat exposure in human males: a longitudinal multi-omics profiling study.  |  Wen, J., et al. 2024. Front Public Health. 12: 1384544. PMID: 38813424

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,5-dehydro Docosahexaenoic Acid, 25 µg

sc-220993
25 µg
$142.00