Date published: 2026-3-15

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4,4′-Trimethylenebis(1-methylpiperidine) (CAS 64168-11-2)

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Alternate Names:
4,4′-(1,3-Propanediyl)bis[1-methyl-piperidine]
CAS Number:
64168-11-2
Molecular Weight:
238.41
Molecular Formula:
C15H30N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4′-Trimethylenebis(1-methylpiperidine), alternatively known as 1,3-bis(1-methylpiperidin-4-yl)propane, is an organic compound that finds utility in diverse scientific research applications. This colorless liquid possesses a faint odor and exhibits a low boiling point. Primarily, this compound serves as a valuable reagent for synthesizing various compounds and acts as a starting material for the creation of other organic compounds. In scientific research, 4,4′-Trimethylenebis(1-methylpiperidine) has found wide-ranging utilization. It serves as a starting material for synthesizing diverse organic compounds, including amino acids, peptides, and nucleosides. Furthermore, it plays a role in the study of enzyme-catalyzed reactions, protein structure, and nucleic acid structure and function. Although the complete mechanism of action of 4,4′-Trimethylenebis(1-methylpiperidine) remains elusive, it is believed to interact with various biological molecules, such as proteins and nucleic acids, through a range of mechanisms. Interactions with proteins are thought to occur via hydrogen bonding and electrostatic interactions. Similarly, interactions with nucleic acids are believed to involve hydrogen bonding, electrostatic interactions, and van der Waals forces.


4,4′-Trimethylenebis(1-methylpiperidine) (CAS 64168-11-2) References

  1. Polycationic Monomeric and Homodimeric Asymmetric Monomethine Cyanine Dyes with Hydroxypropyl Functionality-Strong Affinity Nucleic Acids Binders.  |  Mikulin, I., et al. 2021. Biomolecules. 11: PMID: 34439741
  2. Alkaline Stable Anion Exchange Membranes Based on Cross-Linked Poly(arylene ether sulfone) Bearing Dual Quaternary Piperidines for Enhanced Anion Conductivity at Low Water Uptake.  |  Sharma, PP., et al. 2022. Molecules. 27: PMID: 35056678

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4′-Trimethylenebis(1-methylpiperidine), 50 g

sc-238984
50 g
$163.00