Date published: 2026-3-14

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4,4′-Difluorobenzil (CAS 579-39-5)

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Alternate Names:
4,4′-Difluorobibenzoyl
CAS Number:
579-39-5
Molecular Weight:
246.21
Molecular Formula:
C14H8F2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4′-Difluorobenzil is a chemical compound that is explored in the field of organic chemistry for its applications in the synthesis of various difluorinated aromatic compounds. 4,4′-Difluorobenzil impacts fluorine substitution on the physical and chemical properties of aromatic molecules, such as changes in reactivity and electronic characteristics. It is also a subject of interest in material science, where it is in the preparation of advanced materials that require specific fluorinated structures for enhanced performance. The compound is instrumental in the development of new methodologies, including those that lead to the formation of polymers and small molecules with difluoromethylene units. 4,4′-Difluorobenzil serves as a starting material in the synthesis of ligands for catalysis, where the influence of fluorine atoms on catalytic activity is assessed.


4,4′-Difluorobenzil (CAS 579-39-5) References

  1. Studies on the Condensation Pathway to and Properties of Diiron Azadithiolate Carbonyls.  |  Stanley, JL., et al. 2007. Organometallics. 26: 1907-1911. PMID: 18592045
  2. Catalytic Asymmetric Synthesis of Fluoroalkyl-Containing Compounds by Three-Component Photoredox Chemistry.  |  Ma, J., et al. 2018. Chemistry. 24: 259-265. PMID: 29105857
  3. Detailed quantum mechanical, molecular docking, QSAR prediction, photovoltaic light harvesting efficiency analysis of benzil and its halogenated analogues.  |  Mary, YS., et al. 2019. Heliyon. 5: e02825. PMID: 31763480
  4. Hydroxy-directed fluorination of remote unactivated C(sp3)-H bonds: a new age of diastereoselective radical fluorination.  |  Harry, SA., et al. 2022. Chem Sci. 13: 7007-7013. PMID: 35774162

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4′-Difluorobenzil, 5 g

sc-233034
5 g
$102.00