Date published: 2025-10-15

1-800-457-3801

SCBT Portrait Logo
Seach Input

4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt (CAS 65664-81-5)

5.0(1)
Write a reviewAsk a question

Alternate Names:
Bis-ANS
CAS Number:
65664-81-5
Purity:
≥95%
Molecular Weight:
672.85
Molecular Formula:
C32H22N2O6S2•K2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

DBNPA, scientifically known as 4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt, is a synthetic organic compound extensively utilized in the fields of biochemistry, pha and other scientific disciplines. It presents as a white, odorless, crystalline powder that readily dissolves in water. 4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt finds wide-ranging applications in both in vivo and in vitro experiments, as well as biochemical and physiological studies. n vivo applications involve investigating the impacts of 4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt on the liver, kidney, cardiovascular system, and central nervous system. Similarly, in vitro studies focus on evaluating the effects of 4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt on cell cultures and biochemical assays.


4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt (CAS 65664-81-5) References

  1. How additives influence the refolding of immunoglobulin-folded proteins in a stepwise dialysis system. Spectroscopic evidence for highly efficient refolding of a single-chain Fv fragment.  |  Umetsu, M., et al. 2003. J Biol Chem. 278: 8979-87. PMID: 12519771
  2. Role of ATP on the interaction of alpha-crystallin with its substrates and its implications for the molecular chaperone function.  |  Biswas, A. and Das, KP. 2004. J Biol Chem. 279: 42648-57. PMID: 15292216
  3. The fusogenic state of Mayaro virus induced by low pH and by hydrostatic pressure.  |  Freitas, M., et al. 2006. Cell Biochem Biophys. 44: 325-35. PMID: 16679519
  4. Online fluorescent dye detection method for the characterization of immunoglobulin G aggregation by size exclusion chromatography and asymmetrical flow field flow fractionation.  |  Hawe, A., et al. 2008. Anal Biochem. 378: 115-22. PMID: 18455994
  5. Kinetic instability of the serpin Z alpha1-antitrypsin promotes aggregation.  |  Knaupp, AS., et al. 2010. J Mol Biol. 396: 375-83. PMID: 19944704
  6. Misconceptions over Förster resonance energy transfer between proteins and ANS/bis-ANS: Direct excitation dominates dye fluorescence.  |  Hawe, A., et al. 2010. Anal Biochem. 401: 99-106. PMID: 20197057
  7. Probing bis-ANS binding sites of different affinity on aggregated IgG by steady-state fluorescence, time-resolved fluorescence and isothermal titration calorimetry.  |  Hawe, A., et al. 2011. J Pharm Sci. 100: 1294-305. PMID: 20957745
  8. Simultaneous detection and analysis of protein aggregation and protein unfolding by size exclusion chromatography with post column addition of the fluorescent dye BisANS.  |  Printz, M. and Friess, W. 2012. J Pharm Sci. 101: 826-37. PMID: 22095720
  9. Hsp90 inhibitors as new leads to target parasitic diarrheal diseases.  |  Debnath, A., et al. 2014. Antimicrob Agents Chemother. 58: 4138-44. PMID: 24820073
  10. Sensitive fluorescence-based method for the rapid determination of polysorbate-80 content in therapeutic monoclonal antibody products.  |  Zheng, S., et al. 2015. Pharm Dev Technol. 20: 872-876. PMID: 24946793
  11. Application of BisANS fluorescent dye for developing a novel protein assay.  |  Datki, Z., et al. 2019. PLoS One. 14: e0215863. PMID: 31002721
  12. Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin.  |  Jayaraj, A., et al. 2021. Endocrinology. 162: PMID: 33125473
  13. Thermodynamics of binding of the distal calcium to manganese peroxidase.  |  Sutherland, GR. and Aust, SD. 1997. Biochemistry. 36: 8567-73. PMID: 9214302

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt, 1 mg

sc-214281A
1 mg
$75.00

4,4′-Dianilino-1,1′-binaphthyl-5,5′-disulfonic acid dipotassium salt, 5 mg

sc-214281
5 mg
$160.00