Date published: 2026-4-4

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4,4′-Azobis(4-cyanovaleric acid) (CAS 2638-94-0)

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Alternate Names:
ABCVA; ACVA; 4,4′-Azobis(4-cyanopentanoic acid)
Application:
4,4′-Azobis(4-cyanovaleric acid) is an azo initiator used in radical polymerization processes
CAS Number:
2638-94-0
Purity:
≥97%
Molecular Weight:
280.28
Molecular Formula:
C12H16N4O4
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4′-Azobis(4-cyanovaleric acid), also referred to as 4,4′-Azo-CVA, holds a prominent position as an organic compound. Manifesting as a colorless, crystalline solid, 4,4′-Azobis(4-cyanovaleric acid) exhibits high solubility in both water and organic solvents. Scientific research extensively utilizes 4,4′-Azobis(4-cyanovaleric acid)′-Azo-CVA for a multitude of purposes. Its versatility as a reagent finds particular use in the synthesis of organic and inorganic compounds. Furthermore, it plays a role in the production of polymers and other materials. 4,4′-Azobis(4-cyanovaleric acid)′-Azo-CVA boasts highly reactive properties, enabling it to partake in a diverse array of chemical reactions. Among these, the azo coupling reaction stands as the most prevalent. This reaction entails the coupling of two molecules of 4,4′-Azobis(4-cyanovaleric acid)′-Azo-CVA to generate a novel compound.


4,4′-Azobis(4-cyanovaleric acid) (CAS 2638-94-0) References

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  4. High stability of thermoresponsive polymer-brush-grafted silica beads as chromatography matrices.  |  Nagase, K., et al. 2012. ACS Appl Mater Interfaces. 4: 1998-2008. PMID: 22452297
  5. Coating gigaporous polystyrene microspheres with cross-linked poly(vinyl alcohol) hydrogel as a rapid protein chromatography matrix.  |  Qu, JB., et al. 2014. ACS Appl Mater Interfaces. 6: 12752-60. PMID: 25017479
  6. Consumption of peptide-included and free tryptophan induced by peroxyl radicals: A kinetic study.  |  Fuentes, E. and López-Alarcón, C. 2014. Free Radic Biol Med. 75 Suppl 1: S38. PMID: 26461357
  7. Remotely controlled drug release based on iron oxide nanoparticles for specific therapy of cancer.  |  Wu, L., et al. 2017. Colloids Surf B Biointerfaces. 152: 440-448. PMID: 28183070
  8. Tailored synthesis of polymer-brush-grafted mesoporous silicas with N-halamine and quaternary ammonium groups for antimicrobial applications.  |  Wang, Y., et al. 2019. J Colloid Interface Sci. 533: 604-611. PMID: 30193147
  9. Affinity Capillary Electrochromatography of Molecularly Imprinted Thin Layers Grafted onto Silica Capillaries Using a Surface-Bound Azo-Initiator and Living Polymerization.  |  Giovannoli, C., et al. 2018. Polymers (Basel). 10: PMID: 30966228
  10. Methionine Functionalized Biocompatible Block Copolymers for Targeted Plasmid DNA Delivery.  |  Wu, Y., et al. 2019. J Vis Exp.. PMID: 31449233
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  12. An Alternating Magnetic Field-Controlled Drug Delivery System Based on 4,4'-Azobis (4-cyanovaleric Acid)-Functioned Fe3O4@Chitosan Nanoparticles.  |  Yin, W., et al. 2023. Bioengineering (Basel). 10: PMID: 36829623
  13. Imparting Waterproofing Properties to Leather by Polymer Nanoemulsion Based on Long-Chain Alkyl Acrylate.  |  Jin, L., et al. 2023. Materials (Basel). 16: PMID: 36837094
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  15. Oxidation of human red blood cells by a free radical initiator and effects of radical scavengers.  |  Pekiner, B. and Pennock, JF. 1994. Biochem Mol Biol Int. 33: 1159-67. PMID: 7804142

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4′-Azobis(4-cyanovaleric acid), 5 g

sc-238968B
5 g
$20.00

4,4′-Azobis(4-cyanovaleric acid), 25 g

sc-238968
25 g
$45.00

4,4′-Azobis(4-cyanovaleric acid), 100 g

sc-238968A
100 g
$175.00

4,4′-Azobis(4-cyanovaleric acid), 500 g

sc-238968C
500 g
$877.00

4,4′-Azobis(4-cyanovaleric acid), 1 kg

sc-238968D
1 kg
$1734.00