Molecular structure of 4,4-Difluorocyclohexanamine Hydrochloride, CAS Number: 675112-70-6
4,4-Difluorocyclohexanamine Hydrochloride (CAS 675112-70-6)
Alternate Names:
4,4-difluoro-cyclohexylamine
Application:
4,4-Difluorocyclohexanamine Hydrochloride is an inhibitor of 11-β-hydroxysteroid dehydrogenase 1
CAS Number:
675112-70-6
Molecular Weight:
171.62
Molecular Formula:
C6H12ClF2N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Inhibitors of 11--hydroxysteroid dehydrogenase.
4,4-Difluorocyclohexanamine Hydrochloride (CAS 675112-70-6) References
- Discovery of orally active butyrolactam 11beta-HSD1 inhibitors. | Yeh, VS., et al. 2006. Bioorg Med Chem Lett. 16: 5555-60. PMID: 16931002
- Discovery of a potent, selective, and orally bioavailable acidic 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor: discovery of 2-[(3S)-1-[5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl]-3-piperidyl]acetic acid (AZD4017). | Scott, JS., et al. 2012. J Med Chem. 55: 5951-64. PMID: 22691057
- Lead optimization toward proof-of-concept tools for Huntington's disease within a 4-(1H-pyrazol-4-yl)pyrimidine class of pan-JNK inhibitors. | Wityak, J., et al. 2015. J Med Chem. 58: 2967-87. PMID: 25760409
Inhibitor of:
11beta-HSD1, and Enzyme.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4,4-Difluorocyclohexanamine Hydrochloride, 250 mg | sc-206942 | 250 mg | $400.00 |