Date published: 2026-4-30

1-800-457-3801

SCBT Portrait Logo
Seach Input

4-(4-Aminophenyl)butyric acid (CAS 15118-60-2)

0.0(0)
Write a reviewAsk a question

Alternate Names:
4-(4-aminophenyl)butanoic acid; 4-(4-Aminophenyl)butyricacid
CAS Number:
15118-60-2
Purity:
≥95%
Molecular Weight:
179.22
Molecular Formula:
H2NC6H4(CH2)3CO2H
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

4-(4-Aminophenyl)butyric acid (4-APB) is an organic compound that originates from butanoic acid and occurs naturally or synthetically in various compounds. This chemical holds substantial significance as an intermediary in the production of numerous pharmaceuticals and plays a role in the creation of food additives, dyes, and perfumes. Delving into the realms of biochemistry and physiology, 4-(4-Aminophenyl)butyric acid boasts a range of unique properties that render it a valuable asset in scientific exploration. In the realm of scientific research, 4-(4-Aminophenyl)butyric acid has been employed in various applications. Researchers have utilized it to investigate the impact of drugs on the nervous system, delve into cellular signaling pathways, and explore enzyme-substrate interactions. Furthermore, its inclusion has been vital in unraveling the mechanisms of drug action and understanding how drugs affect the immune system. Despite its widespread use, the precise mechanism of action of 4-(4-Aminophenyl)butyric acid remains elusive. It is thought to function as an agonist at certain G-protein coupled receptors and may also interact with other proteins involved in signal transduction pathways. Additionally, 4-(4-Aminophenyl)butyric acid has been found to inhibit the enzyme monoamine oxidase, which plays a role in neurotransmitter breakdown. 4-(4-Aminophenyl)butyric acid, with its diverse applications and intriguing properties, stands as useful in scientific research, providing valuable insights into numerous aspects of biochemistry and physiology.


4-(4-Aminophenyl)butyric acid (CAS 15118-60-2) References

  1. Isolation of amine oxidase from bovine plasma by a two-step procedure.  |  Vianello, F., et al. 1992. Protein Expr Purif. 3: 362-7. PMID: 1333859
  2. Development of a highly sensitive and specific enzyme-linked immunosorbent assay for detection of Sudan I in food samples.  |  Han, D., et al. 2007. J Agric Food Chem. 55: 6424-30. PMID: 17622156
  3. Structure-activity relationship for thiohydantoin androgen receptor antagonists for castration-resistant prostate cancer (CRPC).  |  Jung, ME., et al. 2010. J Med Chem. 53: 2779-96. PMID: 20218717
  4. Rational design, synthesis, and characterization of highly fluorescent optical switches for high-contrast optical lock-in detection (OLID) imaging microscopy in living cells.  |  Petchprayoon, C., et al. 2011. Bioorg Med Chem. 19: 1030-40. PMID: 20674372
  5. Preparative-scale isoelectric trapping by recursive electrophoresis in a compartmentalized system having orthogonal primary and secondary pH gradients. Part 1--construction and standard operation.  |  North, RY. and Vigh, G. 2011. Electrophoresis. 32: 2797-804. PMID: 21994093
  6. Preparative-scale isoelectric trapping by recursive electrophoresis in a compartmentalized system having orthogonal primary and secondary pH gradients. Part 2--operation in cascade mode.  |  North, RY. and Vigh, G. 2011. Electrophoresis. 32: 2805-8. PMID: 21994126
  7. Anticancer Platinum(IV) Prodrugs Containing Monoaminophosphonate Ester as a Targeting Group Inhibit Matrix Metalloproteinases and Reverse Multidrug Resistance.  |  Huang, X., et al. 2017. Bioconjug Chem. 28: 1305-1323. PMID: 28276682
  8. Electrodeposited Organic Layers Formed from Aryl Diazonium Salts for Inhibition of Copper Corrosion.  |  Chira, A., et al. 2017. Materials (Basel). 10: PMID: 28772600
  9. Grafting of Diazonium Salts on Surfaces: Application to Biosensors.  |  Hetemi, D., et al. 2020. Biosensors (Basel). 10: PMID: 31952195
  10. Photo/Electrocatalytic Hydrogen Peroxide Production by Manganese and Iron Porphyrin/Molybdenum Disulfide Nanoensembles.  |  Perivoliotis, DK., et al. 2022. Small. 18: e2203032. PMID: 35980982
  11. Electrophoretic mobilization in capillary isoelectric focusing by a weak acid or an acidic ampholyte as catholyte assessed by computer simulation.  |  Thormann, W. 2023. Electrophoresis. 44: 656-666. PMID: 36448503
  12. 4-[4-[(2-Hydroxybenzoyl)amino]phenyl]butyric acid as a novel oral delivery agent for recombinant human growth hormone.  |  Leone-Bay, A., et al. 1996. J Med Chem. 39: 2571-8. PMID: 8691455
  13. Acylated non-alpha-amino acids as novel agents for the oral delivery of heparin sodium, USP.  |  Leone-Bay, A., et al. 1998. J Control Release. 50: 41-9. PMID: 9685871

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4-(4-Aminophenyl)butyric acid, 1 g

sc-226372
1 g
$24.00