4,4,5,5-Tetramethyl-2-(4-trifluoromethoxyphenyl)-1,3,2-dioxaborolane (CAS 474709-28-9)

4,4,5,5-Tetramethyl-2-(4-trifluoromethoxyphenyl)-1,3,2-dioxaborolane is a boronic acid based compound, also known as boronate ester. This white crystalline solid demonstrates limited solubility in water but readily dissolves in the majority of organic solvents. Exhibiting excellent thermal stability, the capability to construct stable and reversible complexes with Lewis bases, and notable reactivity with electrophiles, 4,4,5,5-Tetramethyl-2-(4-trifluoromethoxyphenyl)-1,3,2-dioxaborolane emerges as a multifunctional foundational component for organic synthesis. This compound has yielded encouraging outcomes in diverse scientific explorations, encompassing organic synthesis, fluorescence imaging, and catalysis. 4,4,5,5-Tetramethyl-2-(4-trifluoromethoxyphenyl)-1,3,2-dioxaborolane versatility in organic synthesis enables the creation of a spectrum of chemicals, inclusive of those with biological activity. It has also shown potential promise as a fluorescence imaging agent due to its propensity to create stable complexes with a variety of functional groups. Additionally, the application of 4,4,5,5-Tetramethyl-2-(4-trifluoromethoxyphenyl)-1,3,2-dioxaborolane as a catalyst has been investigated in several organic reactions, including but not limited to, Suzuki-Miyaura, Sonogashira, and Heck couplings.