Date published: 2025-10-3

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4,4,4-Trifluorobutylamine (CAS 819-46-5)

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Alternate Names:
4-Amino-1,1,1-trifluorobutane
CAS Number:
819-46-5
Molecular Weight:
127.11
Molecular Formula:
C4H8F3N
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4,4-Trifluorobutylamine finds extensive application in scientific research, serving a multitude of purposes. It proves invaluable as a reagent in organic synthesis, a solvent for synthesizing polymers and other materials, and a catalyst for diverse reactions. In the field of biochemistry, 4,4,4-Trifluorobutylamine assumes roles as a substrate for enzymatic reactions and a reactant within various biochemical pathways. When employed as a reagent in organic synthesis, it acts as a nucleophile, exhibiting a propensity to attack electrophilic sites on molecules. Within biochemical pathways, its function varies depending on the reaction at hand it can serve as a substrate, a co-substrate, or an inhibitor, adapting to the specific requirements of the pathway. The versatility of 4,4,4-Trifluorobutylamine contributes to its significance in both organic synthesis and the intricate workings of biochemical processes.


4,4,4-Trifluorobutylamine (CAS 819-46-5) References

  1. Peptide Conjugation to a Polymer Coating via Native Chemical Ligation of Azlactones for Cell Culture.  |  Schmitt, SK., et al. 2016. Biomacromolecules. 17: 1040-7. PMID: 26835552
  2. Flow Photochemistry as a Tool in Organic Synthesis.  |  Rehm, TH. 2020. Chemistry. 26: 16952-16974. PMID: 32427387

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4,4-Trifluorobutylamine, 1 g

sc-284451
1 g
$220.00

4,4,4-Trifluorobutylamine, 5 g

sc-284451A
5 g
$600.00