Date published: 2026-5-14

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4,4,4-Trifluorobutyl iodide (CAS 461-17-6)

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Alternate Names:
4-Iodo-1,1,1-trifluorobutane; 1-Iodo-4,4,4-trifluorobutane
CAS Number:
461-17-6
Molecular Weight:
237.99
Molecular Formula:
C4H6F3I
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4,4-Trifluorobutyl iodide is a fluorinated alkyl iodide with a wide range of applications in scientific research, including as a reagent in organic synthesis and as a probe for the detection of proteins, nucleic acids, and other biological molecules. It may act to inhibit the activity of enzymes, such as proteases, and to interfere with the binding of proteins to other molecules. In addition, it may act to inhibit the growth of bacteria and to interfere with the function of ion channels.


4,4,4-Trifluorobutyl iodide (CAS 461-17-6) References

  1. Synthesis and activity of novel and selective I(Ks)-channel blockers.  |  Gerlach, U., et al. 2001. J Med Chem. 44: 3831-7. PMID: 11689069
  2. Bridged di(alkyl- and 4,4,4-trifluorobutylimidazolium) quaternary salts based on p-tert-butylcalix[4]arene.  |  Jin, CM. and Shreeve, JM. 2004. Inorg Chem. 43: 7532-8. PMID: 15530104
  3. Scope and limitations of auxiliary-assisted, palladium-catalyzed arylation and alkylation of sp2 and sp3 C-H bonds.  |  Nadres, ET., et al. 2013. J Org Chem. 78: 9689-714. PMID: 24090404
  4. Synthesis of C-14 radiolabeled glucagon receptor antagonist and its use in a human mass balance study.  |  Czeskis, BA. and Satonin, DK. 2017. J Labelled Comp Radiopharm. 60: 110-115. PMID: 27910129

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4,4-Trifluorobutyl iodide, 1 g

sc-262189
1 g
$28.00

4,4,4-Trifluorobutyl iodide, 5 g

sc-262189A
5 g
$69.00