Date published: 2026-7-3

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4,4,4-Trifluorobutan-2-one (CAS 2366-70-3)

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CAS Number:
2366-70-3
Molecular Weight:
126.08
Molecular Formula:
C4H5F3O
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4,4-Trifluorobutan-2-one is a reagent in organic synthesis. It acts as a key intermediate in the production of various fluorinated compounds. Its mechanism of action involves participating in nucleophilic addition reactions, allowing for the introduction of fluorine atoms into organic molecules. In the laboratory setting, 4,4,4-Trifluorobutan-2-one plays a role in the preparation of fluorinated organic molecules.


4,4,4-Trifluorobutan-2-one (CAS 2366-70-3) References

  1. Identification of a new class of potent Cdc7 inhibitors designed by putative pharmacophore model: Synthesis and biological evaluation of 2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-ones.  |  Kurasawa, O., et al. 2017. Bioorg Med Chem. 25: 2133-2147. PMID: 28284870
  2. The Strong β-CF3 Shielding Effect in Hexafluoroisopropanol and 100 Other Organic Solvents Revisited with 17O NMR Spectroscopy.  |  Bernhardt, A., et al. 2018. ChemCatChem. 10: 1547-1551. PMID: 29731952
  3. Copper-Catalyzed Selective Defluorinative Sulfuration of Trifluoropropanamides Leading to α-Fluorothioacrylamides.  |  Shen, XQ., et al. 2021. J Org Chem. 86: 1591-1600. PMID: 33372521

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4,4-Trifluorobutan-2-one, 1 g

sc-262188
1 g
$58.00

4,4,4-Trifluorobutan-2-one, 5 g

sc-262188A
5 g
$160.00