Date published: 2026-2-7

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4,4,4-Trifluoro-DL-valine (CAS 16063-79-9)

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Alternate Names:
2-Amino-3-methyl-4,4,4-trifluorobutanoic acid; 2-Amino-3-methyl-4,4,4-trifluorobutyric acid
CAS Number:
16063-79-9
Purity:
≥97%
Molecular Weight:
171.12
Molecular Formula:
C5H8F3NO2
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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4,4,4-Trifluoro-DL-valine is a fluorinated analog of the amino acid valine and is primarily utilized in biochemical research to study protein structure and function. In particular, it is incorporated into peptides to investigate the impact of fluorination on peptide conformation and stability, due to the electron-withdrawing properties of the trifluoromethyl group. Additionally, 4,4,4-Trifluoro-DL-valine is used in the field of proteomics to modify proteins, which allows scientists to probe protein-protein interactions and enzyme catalysis mechanisms. Researchers also employ this compound to explore its influence on metabolic pathways since the presence of the trifluoromethyl group can alter the usual metabolic processing of amino acids. Furthermore, 4,4,4-Trifluoro-DL-valine serves as a tool in the synthesis of more complex fluorinated compounds that are of interest in various research domains.


4,4,4-Trifluoro-DL-valine (CAS 16063-79-9) References

  1. Trifluoromethoxy-benzylated ligands improve amyloid detection in the brain using (19)F magnetic resonance imaging.  |  Amatsubo, T., et al. 2009. Neurosci Res. 63: 76-81. PMID: 18996420

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

4,4,4-Trifluoro-DL-valine, 250 mg

sc-256835
250 mg
$577.00

4,4,4-Trifluoro-DL-valine, 1 g

sc-256835A
1 g
$1254.00