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Butyrolactone 3, also called MB-3, is an inhibitor of Histone acetyltransferase GCN5 (general control of amino-acid synthesis 5). Gcn5 HAT activity is required to acetylate histone H3 lysine 9 (K9) and K14, which allows transcription elongation by relaxing nucleosomes. Butyrolactone 3 specifically inhibits Gcn5′s HAT activity. It may act to display anti-inflammatory and anti-carcinogenic effects.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(2-Chloro-5-methylphenoxy)-3-fluorophenylamine, 500 mg | sc-313944 | 500 mg | $294.00 |