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SB220025 is a compound that functions as a potent and selective inhibitor of the p38 mitogen-activated protein kinase (MAPK) pathway. It exerts its mechanism of action by targeting and binding to the ATP-binding site of p38 MAPK, thereby preventing its activation and subsequent phosphorylation of downstream substrates. This inhibition ultimately leads to the suppression of pro-inflammatory cytokine production and gene expression. By interfering with the p38 MAPK signaling cascade, SB220025 plays a role in modulating cellular responses to various stress stimuli, including inflammatory and immune responses.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(2,3-Dimethyl-indol-1-yl)-3-hydroxy-butyric acid, 500 mg | sc-314178 | 500 mg | $260.00 |