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D-erythro-N,N-Dimethylsphingosine inhibits SphK (sphingosine kinase), blocking the conversion of sphingosine to sphingosine-1 phosphate. It is an endogenous compound produced via ceramide catabolism. D-erythro-N,N-Dimethylsphingosine is capable of producing EGF-like activity in vitro without the presence of any EFG-2 by stereospecifically inducing EGF receptor autophosphorylation. D-erythro-N,N-Dimethylsphingosine may act to inhibit PKC (protein kinase C), enhance src-kinase activity, and induce apoptosis.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-(2,3-Dihydro-1H-inden-5-yloxy)phenylamine, 500 mg | sc-314170 | 500 mg | $294.00 |