![4-[(3-Formyl-2-pyridinyl)oxy]benzenecarbonitrile - chemical structure image](https://media.scbt.com/product/4--3-formyl-2-pyridinyl-oxybenzenecarbonitrile-structure_23_09_b_230958.jpg)
![4-[(3-Formyl-2-pyridinyl)oxy]benzenecarbonitrile - chemical structure image](https://media.scbt.com/product/4--3-formyl-2-pyridinyl-oxybenzenecarbonitrile-structure_23_09_t_230958.jpg "Molecular structure of 4-[(3-Formyl-2-pyridinyl)oxy]benzenecarbonitrile")
4-[(3-Formyl-2-pyridinyl)oxy]benzenecarbonitrile
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Bisindolylmaleimide V is used as a negative control for the PKC (protein kinase C)-inhibitory activity. Bisindolylmaleimide V, also known as BIM V, exhibits weak inhibition against protein kinase C (PKC) with an IC50 value exceeding 100 µM. Despite its limited potency as a PKC inhibitor, Bisindolylmaleimide V effectively impedes the activation of in vivo mitogen-stimulated protein kinase p70s6k/p85s6k (S6K) with an IC50 value of 8 µM. Functioning as a negative control for PKC inhibitors, Bisindolylmaleimide V serves as an inhibitor of S6K and a safeguard against necrosis. It stands as a cell-permeable compound, valuable for protein kinase C inhibition studies, showcasing an IC50 greater than 100 µM. Its capacity to halt the activation of p70s6k/p85s6k in vivo is demonstrated with an IC50 of 8 µM.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-[(3-Formyl-2-pyridinyl)oxy]benzenecarbonitrile, 500 mg | sc-315180 | 500 mg | $198.00 | |||
4-[(3-Formyl-2-pyridinyl)oxy]benzenecarbonitrile, 1 g | sc-315180A | 1 g | $269.00 |