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Cefsulodin sodium salt hydrate, a third-generation beta-lactam compound and part of the cephems subgroup, exhibits a mechanism consistent with many beta-lactam compounds by blocking the synthesis of bacterial cell walls. It does this through a competitive inhibition of the penicillin-binding proteins (PBPs), specifically interfering with the crosslinking of peptidoglycan chains necessary for cell wall integrity during the final stages of assembly. This action has been observed to affect various bacteria, showcasing a broad-spectrum nature. However, its effectiveness varies, as seen with cefsulodin-resistant mutants of Pseudomonas aeruginosa, suggesting that it targets multiple PBPs, including PBP3, PBP1A, and PBP1B, to exert its effects.
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Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
4-[(2,3-Dihydro-benzo[1,4]dioxine-6-carbonyl)-amino]-butyric acid, 500 mg | sc-315141 | 500 mg | $240.00 |