Date published: 2026-4-19

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[(3R,4S)-3-Methylpyrrolidine-3,4-diyl]dimethanol hydrochloride

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Molecular Weight:
181.66
Molecular Formula:
C7H15NO2•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Coumermycin A1, a cell permeable antibiotic, has been found to be a dimerizing agent that can activate a modified Raf-1 protein and stimulate the mitogen-activated protein kinase cascade. This compound has also been reported to induce autophosphorylation of GyrB-Janus Kinase (JAK) 2 fusion proteins, thus bypassing receptor activation. JAKs are cytoplasmic protein kinases that interact with intracellular domains of cytokine receptors which plays an important role in signal transduction. The activation of JAK is thought to induce cell proliferation. Studies suggest that Coumermycin A1 can inhibit the supercoiling activity of gyrase by binding to the gyrase B subunit.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

[(3R,4S)-3-Methylpyrrolidine-3,4-diyl]dimethanol hydrochloride, 500 mg

sc-322847
500 mg
$450.00