Molecular structure of 3′-O-Methylcytidine, CAS Number: 20594-00-7
3′-O-Methylcytidine (CAS 20594-00-7)
Alternate Names:
3′-O-Methyl-D-cytidine
CAS Number:
20594-00-7
Molecular Weight:
257.24
Molecular Formula:
C10H15N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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3′-O-Methylcytidine is a modified nucleoside, derived from cytidine, and is present in numerous plant and bacterial species. It serves as a structural analog of cytidine, differing by the presence of a methyl group attached to the 3′-hydroxyl group of the sugar moiety. In scientific research, it is utilized as a substrate to study enzymes involved in nucleic acid metabolism, like cytidine kinase and cytidine deaminase. Furthermore, 3′-O-Methylcytidine functions as an inhibitor of DNA polymerase and reverse transcriptase. Additionally, it serves as a probe to investigate the structure and function of ribonucleic acids (RNA) and to study the regulation of gene expression.
3′-O-Methylcytidine (CAS 20594-00-7) References
- The modified nucleosides of tRNAs. II. Synthesis of 2'-O-methylcytidylyl (3'-5') cytidine. | Markiewicz, WT. and Wiewiórowski, M. 1975. Nucleic Acids Res. 2: 951-60. PMID: 167357
- A high-throughput quantitative approach reveals more small RNA modifications in mouse liver and their correlation with diabetes. | Yan, M., et al. 2013. Anal Chem. 85: 12173-81. PMID: 24261999
- Biocatalytic approaches applied to the synthesis of nucleoside prodrugs. | Iglesias, LE., et al. 2015. Biotechnol Adv. 33: 412-34. PMID: 25795057
- Tetrahydroxy stilbene glycoside attenuates acetaminophen-induced hepatotoxicity by UHPLC-Q-TOF/MS-based metabolomics and multivariate data analysis. | Gao, Y., et al. 2021. J Cell Physiol. 236: 3832-3862. PMID: 33111343
- Nucleic acid related compounds. 12. The facile and high-yield stannous chloride catalyzed monomethylation of the cis-glycol system of nucleosides by diazomethane. | Robins, MJ., et al. 1974. J Org Chem. 39: 1891-9. PMID: 4853388
- Mediated transport of nucleosides in human erythrocytes. Accelerative exchange diffusion of uridine and thymidine and specificity toward pyrimidine nucleosides as permeants. | Cass, CE. and Paterson, AR. 1972. J Biol Chem. 247: 3314-20. PMID: 5027755
- Nucleic acid related compounds. II. A rapid and quantitative preparation of 2'-0- and 3'-0-methyl nucleosides. | Naik, SR. and Robins, MJ. 1971. Biochim Biophys Acta. 246: 341-3. PMID: 5132908
- Nucleic acid related compounds. 1. Methylation and transformation of 4-methoxy-2-pyrimidinone 1- -D-ribofuranoside into 2'-O-methyl nucleoside components of ribonucleic acid, their analogs, and derivatives. | Robins, MJ. and Naik, SR. 1971. Biochemistry. 10: 3591-7. PMID: 5146572
- Mass spectral analysis of modified ribonucleosides obtained by degradation of 14 alkali-stable dinucleotides isolated from yeast ribonucleic acid. | Howlett, HA., et al. 1971. Anal Biochem. 39: 429-40. PMID: 5555471
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3′-O-Methylcytidine, 10 mg | sc-283950 | 10 mg | $84.00 | |||
3′-O-Methylcytidine, 25 mg | sc-283950A | 25 mg | $158.00 |