3′-Hydroxytyrosol 3′-glucuronide (CAS 425408-50-0)

3′-Hydroxytyrosol 3′-glucuronide is a metabolite of hydroxytyrosol, a phenolic compound found in olive oil, and is of particular interest in nutrition and metabolic studies. Its role as a conjugated metabolite makes it for understanding the bioavailability and biotransformation of dietary polyphenols. In research, this glucuronide form is investigated for its potential to elucidate the mechanisms of hydroxytyrosol absorption, distribution, and excretion. Studies involving 3′-Hydroxytyrosol 3′-glucuronide often focus on its antioxidant capacity, looking at how it interacts with cellular oxidative stress models. Researchers also use it to examine the impact of glucuronidation on the biological activity of the parent compound, exploring how such modifications may influence its interaction with cellular targets. Furthermore, this compound is employed in the study of enzyme systems responsible for glucuronidation in the liver, such as UDP-glucuronosyltransferases, helping to provide insights into the metabolism of phenolic compounds.