Molecular structure of 3′-Dephosphocoenzyme A, CAS Number: 3633-59-8
3′-Dephosphocoenzyme A (CAS 3633-59-8)
Alternate Names:
Dephospho CoA
Application:
3′-Dephosphocoenzyme A is A chemical reagent that is the direct precursor of coenzyme A. It is used for the synthesis of coenzyme A by bifunctional CoA Synthase.
CAS Number:
3633-59-8
Purity:
≥90%
Molecular Weight:
687.55
Molecular Formula:
C21H35N7O13P2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3′-Dephosphocoenzyme A is a chemical reagent that is the direct precursor of coenzyme A. It is used for the synthesis of coenzyme A by bifunctional CoA Synthase. 3′-Dephosphocoenzyme A can serve as a transcription initiator during in vitro transcription for CoA-RNA synthesis. It falls into the category of purine ribonucleoside diphosphates, which are ribose-linked purine ribonucleotides with a diphosphate group. Hence, it is regarded as a lipid molecule belonging to the fatty ester class.
3′-Dephosphocoenzyme A (CAS 3633-59-8) References
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- Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). | Cho, KI., et al. 2012. Cell Mol Life Sci. 69: 3511-27. PMID: 22821000
- X-ray study of the conformational changes in the molecule of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis during the catalyzed reaction. | Timofeev, V., et al. 2012. Acta Crystallogr D Biol Crystallogr. 68: 1660-70. PMID: 23151631
- Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. | Upadhyay, SK., et al. 2013. Proc Natl Acad Sci U S A. 110: E2239-48. PMID: 23729813
- Transition of phosphopantetheine adenylyltransferase from catalytic to allosteric state is characterized by ternary complex formation in Pseudomonas aeruginosa. | Chatterjee, R., et al. 2016. Biochim Biophys Acta. 1864: 773-86. PMID: 27041211
- Characterization and quantitative analysis of related substances in Coenzyme A by HPLC and LC-MS/MS. | Yang, Y., et al. 2018. J Pharm Biomed Anal. 150: 220-232. PMID: 29253778
- Determining the Bioenergetic Capacity for Fatty Acid Oxidation in the Mammalian Nervous System. | White, CJ., et al. 2020. Mol Cell Biol. 40: PMID: 32123009
- Comparative Evaluation of Data Dependent and Data Independent Acquisition Workflows Implemented on an Orbitrap Fusion for Untargeted Metabolomics. | Barbier Saint Hilaire, P., et al. 2020. Metabolites. 10: PMID: 32325648
- Acyl carrier protein metabolism and regulation of fatty acid biosynthesis by Lactobacillus plantarum. | Sabaitis, JE. and Powell, GL. 1976. J Biol Chem. 251: 4706-12. PMID: 780354
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3′-Dephosphocoenzyme A, 5 mg | sc-214187 | 5 mg | $239.00 | |||
3′-Dephosphocoenzyme A, 25 mg | sc-214187A | 25 mg | $819.00 |