Date published: 2026-3-11

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3′-Deoxyguanosine (CAS 3608-58-0)

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Alternate Names:
3′-dG
Application:
3′-Deoxyguanosine is a complexing ligand for enzymes and receptors to enable structure analysis
CAS Number:
3608-58-0
Molecular Weight:
267.24
Molecular Formula:
C10H13N5O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3′-Deoxyguanosine (3′-dG) is a naturally occurring modified form of guanosine, a purine nucleoside present in DNA and RNA. Extensively studied due to its potential applications across various fields, from biochemistry to medicine. It serves as a key component in the structure and function of DNA and RNA, making it an essential subject of investigation in scientific research. The mechanism of action of 3′-Deoxyguanosine is multifaceted and still not completely comprehended. However, it is understood that 3′-Deoxyguanosine participates in the formation and metabolism of DNA and RNA, highlighting its integral role in these processes. Furthermore, 3′-Deoxyguanosine is involved in protein metabolism and the formation of proteins.


3′-Deoxyguanosine (CAS 3608-58-0) References

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  2. Inhibition of the replication of a hepatitis C virus-like RNA template by interferon and 3'-deoxycytidine.  |  King, RW., et al. 2002. Antivir Chem Chemother. 13: 363-70. PMID: 12718408
  3. Rat brain guanosine binding site. Biological studies and pseudo-receptor construction.  |  Traversa, U., et al. 2003. Bioorg Med Chem. 11: 5417-25. PMID: 14642586
  4. Conformers of guanosines and their vibrations in the electronic ground and excited states, as revealed by double-resonance spectroscopy and ab initio calculations.  |  Nir, E., et al. 2004. Chemphyschem. 5: 131-7. PMID: 14999856
  5. Effects of polyadenylation inhibition on meiosis progression in relation to the polyadenylation status of cyclins A2 and B1 during in vitro maturation of bovine oocytes.  |  Traverso, JM., et al. 2005. Mol Reprod Dev. 71: 107-14. PMID: 15736128
  6. Structure of human PNP complexed with ligands.  |  Canduri, F., et al. 2005. Acta Crystallogr D Biol Crystallogr. 61: 856-62. PMID: 15983407
  7. Synthesis and antiviral evaluation of carbocyclic analogues of 2-amino-6-substituted-purine 3'-deoxyribofuranosides.  |  Shealy, YF., et al. 1987. J Med Chem. 30: 1090-4. PMID: 3035178
  8. The effects of purine nucleoside analogs on the response of the RIF-1 tumor to melphalan in vivo.  |  Horsman, MR., et al. 1986. Int J Radiat Oncol Biol Phys. 12: 801-6. PMID: 3486861
  9. The role in cancer therapy of inhibiting recovery from PLD induced by radiation or bleomycin.  |  Nakatsugawa, S. and Dewey, WC. 1984. Int J Radiat Oncol Biol Phys. 10: 1425-30. PMID: 6206038
  10. PLDR inhibitors: their biological and clinical implications.  |  Nakatsugawa, S., et al. 1984. Br J Cancer Suppl. 6: 43-7. PMID: 6607738
  11. Effects of inhibitors of radiation-induced potentially lethal damage repair on chemotherapy in murine tumors.  |  Nakatsugawa, S. and Sugahara, T. 1982. Int J Radiat Oncol Biol Phys. 8: 1555-9. PMID: 6982887
  12. 3'-Deoxyribonucleotides inhibit eukaryotic DNA primase.  |  Izuta, S., et al. 1996. J Biochem. 119: 1038-44. PMID: 8827435

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3′-Deoxyguanosine, 10 mg

sc-220903
10 mg
$84.00