Date published: 2026-2-7

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3′,5′-Dimethoxy-4′-hydroxyacetophenone (CAS 2478-38-8)

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Alternate Names:
Acetosyringone; 4′-HYDROXY-3′,5′-DIMETHOXYACETOPHENONE
Application:
3′,5′-Dimethoxy-4′-hydroxyacetophenone is a buffer also known as acetosyringone that is used in the synthesis of tetramethoxychalcone and its analogues as anticancer agents in vitro
CAS Number:
2478-38-8
Purity:
≥95%
Molecular Weight:
196.20
Molecular Formula:
C10H12O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3′,5′-Dimethoxy-4′-hydroxyacetophenone is a compound that is involved in research across various fields of chemistry. In organic synthesis, it is valued for its role as an intermediate in the preparation of more complex molecules, often serving as a precursor for the synthesis of compounds with potential applications in materials science. Its structure, which features methoxy and hydroxy groups attached to an acetophenone core, makes it a suitable candidate for studies in the modification of aromatic systems. Researchers may also examine the compound′s potential as a building block in the creation of novel organic compounds, exploring its reactivity under different chemical conditions. In addition, 3′,5′-Dimethoxy-4′-hydroxyacetophenone is used in the study of photophysical properties, where its ability to absorb and emit light is of particular interest for the development of optical materials.


3′,5′-Dimethoxy-4′-hydroxyacetophenone (CAS 2478-38-8) References

  1. Interference by Mes [2-(4-morpholino)ethanesulfonic acid] and related buffers with phenolic oxidation by peroxidase.  |  Baker, CJ., et al. 2007. Free Radic Biol Med. 43: 1322-7. PMID: 17893045
  2. Role of acetosyringone in the accumulation of a set of RNAs in the arbuscular mycorrhiza fungus Glomus intraradices.  |  Flores-Gómez, E., et al. 2008. Int Microbiol. 11: 275-82. PMID: 19204900
  3. Detection of an O-methyltransferase synthesising acetosyringone in methyl jasmonate-treated tobacco cell-suspensions cultures.  |  Negrel, J., et al. 2014. Phytochemistry. 99: 52-60. PMID: 24445177
  4. Acetosyringone, pH and temperature effects on transient genetic transformation of immature embryos of Brazilian wheat genotypes by Agrobacterium tumefaciens.  |  Manfroi, E., et al. 2015. Genet Mol Biol. 38: 470-6. PMID: 26537604
  5. Synergistic Action of D-Glucose and Acetosyringone on Agrobacterium Strains for Efficient Dunaliella Transformation.  |  Srinivasan, R. and Gothandam, KM. 2016. PLoS One. 11: e0158322. PMID: 27351975
  6. A pattern-triggered immunity-related phenolic, acetosyringone, boosts rapid inhibition of a diverse set of plant pathogenic bacteria.  |  Szatmári, Á., et al. 2021. BMC Plant Biol. 21: 153. PMID: 33765920
  7. Lignin-Derived Syringol and Acetosyringone from Palm Bunch Using Heterogeneous Oxidative Depolymerization over Mixed Metal Oxide Catalysts under Microwave Heating.  |  Panyadee, R., et al. 2021. Molecules. 26: PMID: 34946525
  8. Antioxidant properties of phenolic compounds in macadamia nuts  |  Quinn, L. A., & Tang, H. H. 1996. ournal of the American Oil Chemists' Society. 73: 1585-1588.
  9. Distribution of phenolic compounds in the seagrass Posidonia oceanica  |  Agostini, S., Desjobert, J. M., & Pergent, G. 1998. Phytochemistry. 48(4): 611-617.
  10. Simple method for synthesizing phenolicβ-O-4 dilignols  |  Kawai, S., Okita, K., Sugishita, K., Tanaka, A., & Ohash, H. 1999. Journal of wood science. 45: 440-443.
  11. Agrobacterium-Mediated Genetic Transformation of Switchgrass  |  Somleva, M. N., Tomaszewski, Z., & Conger, B. V. 2002. Crop Science,. 42(6): 2080-2087.
  12. Polymer-Supported Electron-Rich Oxime Palladacycle as an Efficient Heterogeneous Catalyst for the Suzuki Coupling Reaction  |  Cho, H. J., Jung, S., Kong, S., Park, S. J., Lee, S. M., & Lee, Y. S. 2014. Advanced Synthesis & Catalysis. 356(5): 1056-1064.
  13. Selective hydrodeoxygenation of acetophenone derivatives using a Fe25Ru75@SILP catalyst: a practical approach to the synthesis of alkyl phenols and anilines  |  Goclik, L., Walschus, H., Bordet, A., & Leitner, W. 2022. Green Chemistry. 24(7): 2937-2945.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3′,5′-Dimethoxy-4′-hydroxyacetophenone, 1 g

sc-238721
1 g
$57.00

3′,5′-Dimethoxy-4′-hydroxyacetophenone, 5 g

sc-238721A
5 g
$171.00

3′,5′-Dimethoxy-4′-hydroxyacetophenone, 25 g

sc-238721B
25 g
$612.00

3′,5′-Dimethoxy-4′-hydroxyacetophenone, 100 g

sc-238721C
100 g
$1144.00