Molecular structure of 3′,4′-Dimethoxyflavone, CAS Number: 4143-62-8
3′,4′-Dimethoxyflavone (CAS 4143-62-8)
Application:
3′,4′-Dimethoxyflavone is a competitive antagonist of the AhR
CAS Number:
4143-62-8
Purity:
97%
Molecular Weight:
282.30
Molecular Formula:
C17H14O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3,4′-Dimethoxyflavone, a flavonoid compound, naturally occurs in diverse plant sources, such as Ginkgo biloba, citrus fruits, and several medicinal herbs. This compound has garnered attention in the scientific realm, where its properties have been explored. Among its potential applications, it has been scrutinized as an anti-cancer agent, with in vitro studies revealing its ability to impede the growth of cancer cells. Furthermore, scientists have investigated its capacity to regulate the activity of enzymes and receptors involved in various physiological processes.
3′,4′-Dimethoxyflavone (CAS 4143-62-8) References
- 3',4'-dimethoxyflavone as an aryl hydrocarbon receptor antagonist in human breast cancer cells. | Lee, JE. and Safe, S. 2000. Toxicol Sci. 58: 235-42. PMID: 11099636
- Identification through high-throughput screening of 4'-methoxyflavone and 3',4'-dimethoxyflavone as novel neuroprotective inhibitors of parthanatos. | Fatokun, AA., et al. 2013. Br J Pharmacol. 169: 1263-78. PMID: 23550801
- 3',4'-Dimethoxyflavone and valproic acid promotes the proliferation of human hematopoietic stem cells. | Kaur, K., et al. 2013. Stem Cell Res Ther. 4: 60. PMID: 23706670
- Oxidation of 3'-methoxyflavone, 4'-methoxyflavone, and 3',4'-dimethoxyflavone and their derivatives having 5,7-dihydroxyl moieties by human cytochromes P450 1B1 and 2A13. | Shimada, T., et al. 2022. Xenobiotica. 52: 134-145. PMID: 35387543
- A structure activity relationship study of 3,4'-dimethoxyflavone for ArlRS inhibition in Staphylococcus aureus. | Weig, AW., et al. 2023. Org Biomol Chem. 21: 3373-3380. PMID: 37013457
Inhibitor of:
Ah Receptor.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3′,4′-Dimethoxyflavone, 100 mg | sc-267005 | 100 mg | $104.00 |