Molecular structure of 3β,21-Dihydroxy-5α-pregnan-20-one, CAS Number: 567-01-1
3β,21-Dihydroxy-5α-pregnan-20-one (CAS 567-01-1)
Alternate Names:
3β,5α-Tetrahydrodeoxycorticosterone; Epiallopregnanolone
Application:
3β,21-Dihydroxy-5α-pregnan-20-one is a unique steroid
CAS Number:
567-01-1
Molecular Weight:
334.49
Molecular Formula:
C21H34O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3β,21-Dihydroxy-5α-pregnan-20-one is a sterol derivative that is structurally related to other progesterone-type sterols that have been shown to be neuroactive and are thought to regulate various physiological functions. One study showed that some neuroactive steroids can sensitize GABA receptors to its corresponding ligand - gamma-amino butyric acid.
3β,21-Dihydroxy-5α-pregnan-20-one (CAS 567-01-1) References
- The effects of neurosteroids on rat behavior and 3H-muscimol binding in the brain. | Członkowska, AI., et al. 1999. Pharmacol Biochem Behav. 63: 639-46. PMID: 10462193
- Suppressing aggressive behavior with analogs of allopregnanolone (epalon). | Slavíková, B., et al. 2001. Steroids. 66: 99-105. PMID: 11146089
- [Proceedings: Study of a new steroid: the 3beta,5alpha-tetrahydro-deoxycorticosterone (3alpha,5beta-tetrahydro-DOC). Its significance during pregnancy (author's transl)]. | Pasqualini, JR., et al. 1975. Ann Endocrinol (Paris). 36: 97-8. PMID: 1190725
- Biotransformation of 21-O-acetyl-deoxycorticosterone by cell suspension cultures of Digitalis lanata (strain W.1.4). | de Pádua, RM., et al. 2012. Steroids. 77: 1373-80. PMID: 22917633
- Steroids in germfree and conventional rats. 21-dehydroxylation by intestinal microorganisms. | Eriksson, H., et al. 1969. Eur J Biochem. 9: 550-4. PMID: 5806503
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3β,21-Dihydroxy-5α-pregnan-20-one, 5 mg | sc-232197 | 5 mg | $61.00 |