3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid (CAS 129768-28-1)
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3-(Trifluoromethyl)-1H-pyrazole-5-carboxylic acid is a chemical compound characterized by the presence of a pyrazole ring, a five-membered heterocyclic structure containing two nitrogen atoms, which is further substituted with a trifluoromethyl group (-CF3) at the 3-position and a carboxylic acid group (-COOH) at the 5-position. This molecular configuration imbues the compound with unique chemical properties and reactivity, making it a valuable intermediate in the synthesis of a wide array of chemical entities. The trifluoromethyl group is highly electronegative, significantly influencing the electronic distribution within the molecule, thereby affecting its reactivity and interaction with biological systems. This property is particularly beneficial in medicinal chemistry, where the introduction of a trifluoromethyl group can enhance the metabolic stability, lipophilicity, and bioavailability.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-(trifluoromethyl)-1H-pyrazole-5-carboxylic acid, 100 mg | sc-288856 | 100 mg | $568.00 |