Date published: 2026-5-25

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3-Thiatetradecanoic Acid (CAS 116296-31-2)

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Alternate Names:
3-TDA
Application:
3-Thiatetradecanoic Acid is an activator of PPAR
CAS Number:
116296-31-2
Molecular Weight:
246.4
Molecular Formula:
C13H26O2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Thiatetradecanoic acid (3-thia TDA) is an analog of the 14-carbon saturated fatty acid myristic acid, wherein the C-3 carbon has been replaced by sulfur in a thioether linkage. When chronically administered to rats, 3-thia TDA acts as a peroxisome inducer (PPAR ligand), increases fatty acid oxidation, and lowers plasma lipid levels.1 Incorporation of 3-thia TDA into dietary regimens at 150 and 300 mg/kg in rats induces the formation of oleic acid via Δ9-desaturase, and dose-dependently augments Δ9-desaturase mRNA levels.2


3-Thiatetradecanoic Acid (CAS 116296-31-2) References

  1. Silver cationization of thia fatty acids and esters in laser desorption/ionization time-of-flight mass spectrometry.  |  Owega, S. and Lai, EP. 1999. J Mass Spectrom. 34: 872-9. PMID: 10423568
  2. Synthesis and antifungal properties of alpha-methoxy and alpha-hydroxyl substituted 4-thiatetradecanoic acids.  |  Carballeira, NM., et al. 2007. Chem Phys Lipids. 150: 82-8. PMID: 17662704

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Thiatetradecanoic Acid, 1 mg

sc-205115
1 mg
$50.00

3-Thiatetradecanoic Acid, 5 mg

sc-205115A
5 mg
$226.00