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Pepstatin A inhibits the aspartic proteases cathepsin D, pepsin, and renin. Additionally, Pepstatin A suppresses p53-dependent apoptosis in lymphoid cells as well as TNFα-induced apoptosis in U937 cells. Pepstatin A also efficiently inhibits HIV-1 protease and Fcgamma receptor induction by IFN-gamma. Pepstatin A is a bacterial-derived chemotactic pentapeptide which is irreversibly inhibits aspartic proteases. Pepstatin A is also used as a research tool in studies of protease mechanisms and biological functions.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-(tert-Butyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole, 500 mg | sc-310370 | 500 mg | $146.00 | |||
3-(tert-Butyl)-5-(4-nitrophenyl)-1,2,4-oxadiazole, 1 g | sc-310370A | 1 g | $203.00 |