Molecular structure of (3-Phenylpropyl)triphenylphosphonium bromide, CAS Number: 7484-37-9
(3-Phenylpropyl)triphenylphosphonium bromide (CAS 7484-37-9)
CAS Number:
7484-37-9
Molecular Weight:
461.39
Molecular Formula:
C27H26BrP
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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(3-Phenylpropyl)triphenylphosphonium bromide, a quaternary ammonium salt synthesized by Michael J. Perkins and colleagues in 1963, has become an invaluable tool in various scientific research studies. Among its applications, it functions as a mitochondrial uncoupler, disrupting the proton gradient across the mitochondrial inner membrane, leading to increased oxygen consumption and ATP production. Additionally, it serves as a protonophore, facilitating the transport of protons across biological membranes, making it suitable for studying membrane potential and ion transport. Furthermore, this compound acts as a fluorescent probe, enabling real-time monitoring of changes in membrane potential.
(3-Phenylpropyl)triphenylphosphonium bromide (CAS 7484-37-9) References
- Arylphosphonium salts interact with DNA to modulate cytotoxicity. | Bergeron, KL., et al. 2009. Mutat Res. 673: 141-8. PMID: 19429515
- Novel chiral (salen)Mn(III) complexes containing a calix[4]arene unit in 1,3-alternate conformation as catalysts for enantioselective epoxidation reactions of (Z)-aryl alkenes. | Bonaccorso, C., et al. 2014. Dalton Trans. 43: 2183-93. PMID: 24297211
- Targeting the Src Homology 2 (SH2) Domain of Signal Transducer and Activator of Transcription 6 (STAT6) with Cell-Permeable, Phosphatase-Stable Phosphopeptide Mimics Potently Inhibits Tyr641 Phosphorylation and Transcriptional Activity. | Mandal, PK., et al. 2015. J Med Chem. 58: 8970-84. PMID: 26506089
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(3-Phenylpropyl)triphenylphosphonium bromide, 10 g | sc-266836 | 10 g | $87.00 |