Molecular structure of 3-O-Acetyl-betulinic acid, CAS Number: 10376-50-8
3-O-Acetyl-betulinic acid (CAS 10376-50-8)
Alternate Names:
3β-Acetoxybetulinic acid
Application:
3-O-Acetyl-betulinic acid is a betulinic acid derivative that shows cytotoxic activity on human cancer cell lines
CAS Number:
10376-50-8
Molecular Weight:
498.8
Molecular Formula:
C32H50O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
3-O-Acetyl-betulinic acid shows cytotoxic activity on human cancer cell lines.
3-O-Acetyl-betulinic acid (CAS 10376-50-8) References
- Synthesis and cytotoxic activity of 3-O-acyl/3-hydrazine /2-bromo/20,29-dibromo betulinic acid derivatives. | Mukherjee, R., et al. 2004. Bioorg Med Chem Lett. 14: 4087-91. PMID: 15225732
- Synthesis of A-seco derivatives of betulinic acid with cytotoxic activity. | Urban, M., et al. 2004. J Nat Prod. 67: 1100-5. PMID: 15270560
- Synthesis of lupane-type saponins bearing mannosyl and 3,6-branched trimannosyl residues and their evaluation as anticancer agents. | Cmoch, P., et al. 2008. Carbohydr Res. 343: 995-1003. PMID: 18328468
- Anticancer activity of 3-O-acylated betulinic acid derivatives obtained by enzymatic synthesis. | Ahmad, FB., et al. 2010. Biosci Biotechnol Biochem. 74: 1025-9. PMID: 20460723
- Synthesis and studies of anticancer properties of lupane-type triterpenoid derivatives containing a cisplatin fragment. | Emmerich, D., et al. 2014. Eur J Med Chem. 75: 460-6. PMID: 24561674
- Betulinic acid derived hydroxamates and betulin derived carbamates are interesting scaffolds for the synthesis of novel cytotoxic compounds. | Wiemann, J., et al. 2015. Eur J Med Chem. 106: 194-210. PMID: 26547057
- A 3D-QSAR Study on Betulinic Acid Derivatives as Anti-Tumor Agents and the Synthesis of Novel Derivatives for Modeling Validation. | Ding, W., et al. 2017. Anticancer Agents Med Chem. 17: 566-575. PMID: 27658994
- Design, Synthesis and Biological Evaluation of Betulinic Acid Derivatives as New Antitumor Agents for Leukemia. | Waechter, F., et al. 2017. Anticancer Agents Med Chem. 17: 1777-1785. PMID: 28403779
- Betulinic acid derived amides are highly cytotoxic, apoptotic and selective. | Hoenke, S., et al. 2020. Eur J Med Chem. 207: 112815. PMID: 32956968
- Apoptotic activity of substituted 3-O-acetyl-betulinic acid benzylamides | Marie Kozubek a, Linda Höhlich a, Sophie Hoenke a, Hans-Peter Deigner b, Ahmed Al-Harrasi c, René Csuk a. 2021. European Journal of Medicinal Chemistry Reports. 3.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
3-O-Acetyl-betulinic acid, 5 mg | sc-202017 | 5 mg | $23.00 | |||
3-O-Acetyl-betulinic acid, 25 mg | sc-202017A | 25 mg | $70.00 |