Date published: 2026-4-4

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3-Nitrophthalhydrazide (CAS 3682-15-3)

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Alternate Names:
2,3-Dihydro-5-nitro-1,4-phthalazinedione
Application:
3-Nitrophthalhydrazide is a hydrazide used for proteomics research
CAS Number:
3682-15-3
Purity:
≥97%
Molecular Weight:
207.14
Molecular Formula:
C8H5N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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3-Nitrophthalhydrazide (5-NO2-DHD) is a nitro-containing heterocyclic compound and a structural analog of phenytoin. Although the precise mechanism of action of 3-Nitrophthalhydrazideis not fully elucidated, it is believed to exert its effects through the inhibition of cyclooxygenase-2 (COX-2), an enzyme involved in the production of inflammatory mediators. Furthermore, this compound has shown inhibitory activity against other enzymes implicated in the production of inflammatory mediators, such as lipoxygenase and cyclooxygenase-1 (COX-1).


3-Nitrophthalhydrazide (CAS 3682-15-3) References

  1. New monoacylhydrazidate-coordinated Mn2+ and Pb2+ compounds.  |  Jin, J., et al. 2012. Dalton Trans. 41: 6137-47. PMID: 22495333
  2. New Zn²⁺ coordination polymers constructed from acylhydrazidate molecules: synthesis and structural characterization.  |  Wang, YN., et al. 2014. Dalton Trans. 43: 15617-27. PMID: 25208479
  3. 3-Aminophthalhydrazide (Luminol) As a Matrix for Dual-Polarity MALDI MS Imaging.  |  Li, B., et al. 2019. Anal Chem. 91: 8221-8228. PMID: 31149814

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

3-Nitrophthalhydrazide, 25 g

sc-231888
25 g
$210.00